GADD45 alleviates acetaminophen-induced hepatotoxicity by promoting AMPK activation

Li, CM; Ming, YN; Wang, ZY; Xu, QL; Yao, LF; Xu, DK; Tang, YY; Lei, XH; Li, XB; Mao, YM

Mao, YM (reprint author), Shanghai Jiao Tong Univ, Shanghai Inst Digest Dis, Sch Med, Div Gastroenterol & Hepatol,Renji Hosp, Shanghai, Peoples R China.; Li, XB (reprint author), Fudan Univ, Sch Basic Med Sci, Dept Physiol & Pathophysiol, Shanghai 200032,

CELLULAR AND MOLECULAR LIFE SCIENCES, 2019; 76 (1): 129

Abstract

As an analgesic and antipyretic drug, acetaminophen (APAP) is commonly used and known to be safe at therapeutic doses. In many countries, the overuse ......

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