A brainstem-central amygdala circuit underlies defensive responses to learned threats

Gu, YR; Piper, WT; Branigan, LA; Vazey, EM; Aston-Jones, G; Lin, LN; LeDoux, JE; Sears, RM

LeDoux, JE (corresponding author), East China Normal Univ, Inst Brain Funct Genom, Sch Life Sci, Shanghai Key Lab Brain Funct Genom,Minist Educ,NY, Shanghai, Peoples R China.; LeDoux, JE; Sears, RM (corresponding author), NYU, Ctr Neural Sci, New York, NY 10003 USA.; LeDoux, JE; Sears, RM (corresponding author), Nathan S Kline Inst Psychiat Res, Emot Brain Inst, Orangeburg, NY 10962 USA.; Sears, RM (corresponding author), NYU, Dept Child & Adolescent Psychiat, Langone Sch Med, New York, NY 10003 USA.

MOLECULAR PSYCHIATRY, 2020; 25 (3): 640

Abstract

Norepinephrine (NE) plays a central role in the acquisition of aversive learning via actions in the lateral nucleus of the amygdala (LA) [1, 2]. Howev......

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