Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLC gamma 1 axis

Xu, JH; Zhong, YF; Yin, HY; Linneman, J; Luo, YX; Xia, SJ; Xia, QY; Yang, L; Huang, XT; Kang, K; Wang, J; Niu, YQ; Li, L; Gou, DM

Gou, DM (通讯作者)，Shenzhen Univ, Coll Life Sci & Oceanog, 1066 Xueyuan Rd, Shenzhen 518060, Guangdong, Peoples R China.

JOURNAL OF HYPERTENSION, 2022; 40 (9): 1795

Abstract

Objective: Pulmonary hypertension is a lethal disease characterized by pulmonary vascular remodeling and is mediated by abnormal proliferation and mig......

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