Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection

Tang, DB; Zhao, HQ; Wu, YM; Peng, B; Gao, ZC; Sun, YY; Duan, JZ; Qi, YH; Li, YF; Zhou, ZM; Guo, GL; Zhang, Y; Li, C; Sui, JH; Li, WH

Li, WH (corresponding author), Natl Inst Biol Sci, Beijing, Peoples R China.; Li, WH (corresponding author), Tsinghua Univ, Tsinghua Inst Multidisciplinary Biomed Res, Beijing, Peoples R China.

CELL REPORTS, 2021; 35 (13):

Abstract

The hepatitis B virus (HBV) infects 257 million people worldwide. HBV infection requires establishment and persistence of covalently closed circular (......

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