PPAR-alpha agonists acutely inhibit Ca2+-independent PLA(2) to reduce H2O2-induced contractions in aortae of spontaneously hypertensive rats

Chen, H; Man, RYK; Leung, SWS

Leung, SWS (reprint author), Li Ka Shing Fac Med, Dept Pharmacol & Pharm, Lab Block,21 Sassoon Rd, Pokfulam, Hong Kong, Peoples R China.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2018; 314 (3): H681

Abstract

Hypertension is associated with endothelial dysfunction, which favors the release of endothelium-derived contracting factors, including vasoconstricto......

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