High-efficiency c-Myc-mediated induction of functional hepatoblasts from the human umbilical cord mesenchymal stem cells

Deng, J; Luo, K; Xu, PC; Jiang, QY; Wang, Y; Yao, YQ; Chen, XL; Cheng, FY; Xie, D; Deng, HX

Xie, D; Deng, HX (corresponding author), Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Peoples R China.; Xie, D; Deng, HX (corresponding author), Sichuan Univ, West China Hosp, Canc Ctr, Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Peoples R China.; Xie, D (corresponding author), Sichuan Univ, West China Hosp, Natl Frontier Ctr Dis Mol Network, Chengdu 610041, Peoples R China.

STEM CELL RESEARCH & THERAPY, 2021; 12 (1):

Abstract

BackgroundDirect reprogramming of human fibroblasts to hepatocyte-like cells was proposed to generate large-scale functional hepatocytes demanded by l......

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