Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2

Yu, PL; Xue, XW; Zhang, JM; Hu, XP; Wu, Y; Jiang, LH; Jin, HW; Luo, JH; Zhang, LR; Liu, ZM; Yang, W

Yang, W (reprint author), Zhejiang Univ, Sch Med, Minist Hlth China, Dept Neurobiol,Key Lab Med Neurobiol, Hangzhou 310058, Zhejiang, Peoples R China.; Liu, ZM (reprint author), Peking Univ, Sch Pharmaceut Sci, State Key Lab Nat & Biomimet Drugs, Beijing

JOURNAL OF GENERAL PHYSIOLOGY, 2017; 149 (2): 219

Abstract

Activation of the transient receptor potential melastatin 2 (TRPM2) channel occurs during the response to oxidative stress under physiological conditi......

Full Text Link