GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3 beta/beta-catenin signaling-MedSci.cn

GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3 beta/beta-catenin signaling

Wang, Y; Chen, S; Xu, Z; Chen, ST; Yao, WB; Gao, XD

Yao, WB; Gao, XD (reprint author), China Pharmaceut Univ, Jiangsu Key Lab Druggabil Biopharmaceut, State Key Lab Nat Med, Sch Life Sci & Technol, Nanjing 210009, Jiangsu, Peoples R China.

NEUROPHARMACOLOGY, 2018; 131 (): 190

Abstract

Alterations of glycoprotein glycans contribute to a wide variety of diseases. Bisecting N-acetylglucosamine (GIcNAc) levels increased in the cerebrosp......

Full Text Link