Coactivation of NF-kappa B and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

Xiu, Y; Dong, QZ; Fu, L; Bossler, A; Tang, XB; Boyce, B; Borcherding, N; Leidinger, M; Sardina, JL; Xue, HH; Li, QC; Feldman, A; Aifantis, I; Boccalatte, F; Wang, LL; Jin, ML; Khoury, J; Wang, W; Hu, SM; Yuan, YZ; Wang, ED; Yuan, J; Janz, S; Colgan, J; Habelhah, H; Waldschmidt, T; Muschen, M; Bagg, A; Darbro, B; Zhao, C

Zhao, C (corresponding author), 25 South Grand Ave,1163 Med Labs, Iowa City, IA 52242 USA.

BLOOD, 2020; 135 (2): 108

Abstract

NF-kappa B and Notch signaling can be simultaneously activated in a variety of B-cell lymphomas. Patients with B-cell lymphoma occasionally develop cl......

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