Chemical activation of SAT1 corrects diet-induced metabolic syndrome

Castoldi, F; Hyvonen, MT; Durand, S; Aprahamian, F; Sauvat, A; Malik, SA; Baracco, EE; Vacchelli, E; Opolon, P; Signolle, N; Lefevre, D; Bossut, N; Eisenberg, T; Dammbrueck, C; Pendl, T; Kremer, M; Lachkar, S; Einer, C; Michalke, B; Zischka, H; Madeo, F; Keinanen, TA; Maiuri, MC; Pietrocola, F; Kroemer, G

Kroemer, G (corresponding author), Univ Paris, Sorbonne Univ, Team Metab Canc & Immun, Ctr Rech Cordeliers,INSERM U1138, Paris, France.; Kroemer, G (corresponding author), Gustave Roussy, Metabol & Cell Biol Platforms, Canc Campus, Villejuif, France.; Pietrocola, F (corresponding author), Karolinska Inst, Dept Biosci & Nutr, Huddinge, Sweden.; Kroemer, G (corresponding author), Hop Europeen Georges Pompidou, AP HP, Pole Biol, Paris, France.; Kroemer, G (corresponding author), Chinese Acad Med Sci, Suzhou Inst Syst Med, Suzhou, Peoples R China.; Kroemer, G (corresponding author), Karolinska Univ Hosp, Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden.

CELL DEATH AND DIFFERENTIATION, 2020; 27 (10): 2904

Abstract

The pharmacological targeting of polyamine metabolism is currently under the spotlight for its potential in the prevention and treatment of several ag......

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