PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Triggers Vascular Smooth Muscle Cell Senescence and Apoptosis: Implication of Its Direct Role in Degenerative Vascular Disease

Guo, YN; Tang, ZH; Yan, BJ; Yin, H; Tai, S; Peng, J; Cui, YT; Gui, Y; Belke, D; Zhou, SH; Zheng, XL

Zhou, SH (通讯作者),139 Middle Renmin Rd, Changsha 410011, Hunan, Peoples R China.;Zheng, XL (通讯作者),GAA12-HRIC 3280 Hosp Dr NW, Calgary, AB T2N 4Z6, Canada.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (1): 67

Abstract

Objective: PCSK9 (proprotein convertase subtilisin/kexin type 9) plays a critical role in cholesterol metabolism via the PCSK9-LDLR (low-density lipop......

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