An expansion study of genotype-driven weekly irinotecan and capecitabine in combination with neoadjuvant radiotherapy for locally advanced rectal cancer with UGT1A1*1*1 genotype

Guan, Y; Shen, YZ; Xu, Y; Li, C; Wang, JW; Gu, WL; Lian, P; Huang, D; Cai, SJ; Zhang, Z; Zhu, J

Zhang, Z; Zhu, J (reprint author), Fudan Univ, Dept Radiat Oncol, Shanghai Canc Ctr, 270 Dongan Rd, Shanghai 200032, Peoples R China.; Zhang, Z; Zhu, J (reprint author), Fudan Univ, Shanghai Med Coll, Dept Oncol, Shanghai 200032, Peoples R China.

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY, 2019; 12 ():

Abstract

Background: In our previous dose-escalation study, we uncovered the maximum tolerated dose (MTD) of weekly irinotecan was escalated to 80 mg/m(2) and ......

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