Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5 '-deoxy-5-fluorocytidine, 5 '-deoxy-5-fluorouridine, and 5-fluorouracil-MedSci.cn

Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5 '-deoxy-5-fluorocytidine, 5 '-deoxy-5-fluorouridine, and 5-fluorouracil

Sekido, M; Fujita, K; Kubota, Y; Ishida, H; Takahashi, T; Ohkuma, R; Tsunoda, T; Ishikawa, F; Shibanuma, M; Sasaki, Y

Fujita, K (reprint author), Showa Univ, Sch Pharm, Dept Pharmaceut Sci, Div Canc Cell Biol,Shinagawa Ku, 1-5-8 Hatanodai, Tokyo 1428555, Japan.

Abstract

PurposeSeveral retrospective studies have shown that the antitumor efficacy of capecitabine-containing chemotherapy decreases when co-administered wit......

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Rabeprazole intake does not affect systemic exposure to capecitabine and its metabolites, 5 '-deoxy-5-fluorocytidine, 5 '-deoxy-5-fluorouridine, and 5-fluorouracil

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