Age-dependent effects of floxuridine (FUdR) on senescent pathology and mortality in the nematode Caenorhabditis elegans

Wang, HY; Zhao, Y; Zhang, ZZ

Zhang, ZZ (reprint author), Harbin Inst Technol, Sch Chem & Chem Engn, Harbin 150001, Heilongjiang, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019; 509 (3): 694

Abstract

Floxuridine (5'-fluorodeoxyuridine, FUdR) acts as an inhibitor of DNA replication by binding to thymidylate synthase and is widely used to treat color......

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