Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains

Pan, M; Zheng, QY; Ding, S; Zhang, LJ; Qu, Q; Wang, T; Hong, DN; Ren, YJ; Liang, LJ; Chen, CL; Mei, ZQ; Liu, L

Liu, L (reprint author), Tsinghua Univ, Tsinghua Peking Ctr Life Sci, MOE Key Lab Bioorgan Phosphorus Chem & Chem Biol, Dept Chem,Ctr Synthet & Syst Biol, Beijing 100084, Peoples R China.; Mei, ZQ (reprint author), Chinese Acad Agr Sci, Biotechnol Res Ins

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019; 58 (9): 2627

Abstract

New synthetic strategies that exploited the strengths of both chemoselective ligation and recombinant protein expression were developed to prepare K27......

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