Enhanced dissolution of solid dispersions containing bicalutamide subjected to mechanical stress

Szafraniec, J; Antosik, A; Knapik-Kowalczuk, J; Chmiel, K; Kurek, M; Gawlak, K; Paluch, M; Jachowicz, R

Szafraniec, J (reprint author), Jagiellonian Univ, Coll Med, Fac Pharm, Dept Pharmaceut Technol & Biopharmaceut,Med 9, PL-30688 Krakow, Poland.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018; 542 (1-2): 18

Abstract

The anticancer drug bicalutamide was co-milled with either Macrogol 6000 or Poloxamer 407, and the physicochemical parameters that drive the phase tra......

Full Text Link