T cell receptors employ diverse strategies to target a p53 cancer neoantigen

Wu, DC; Gowathaman, R; Pierce, BG; Mariuzza, RA

Mariuzza, RA (通讯作者)，Univ Maryland, WM Keck Lab Struct Biol, Inst Biosci & Biotechnol Res, Rockville, MD USA.;Mariuzza, RA (通讯作者)，Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2022; 298 (3):

Abstract

Adoptive cell therapy with tumor-specific T cells can mediate durable cancer regression. The prime target of tumor specific T cells are neoantigens ar......

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