Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LO Delta 13, 5-LO Delta 4 and 5-LOp12

Ball, AK; Beilstein, K; Wittmann, S; Surun, D; Saul, MJ; Schnutgen, F; Flamand, N; Capelo, R; Kahnt, AS; Frey, H; Schaefer, L; Marschalek, R; Hafner, AK; Steinhilber, D

Hafner, AK; Steinhilber, D (reprint author), Goethe Univ Frankfurt, Inst Pharmaceut Chem, Max von Laue Str 9, D-60438 Frankfurt, Germany.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2017; 1862 (5): 561

Abstract

Human 5-lipoxygenase (5-LO-WT) initiates the leukotriene (LT) biosynthesis. LTs play an important role in diseases like asthma, atherosclerosis and in......

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