Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy

Tang, K; Wu, YH; Song, YH; Yu, B

Yu, B (corresponding author), Zhengzhou Univ, Minist Educ, Sch Pharmaceut Sci, Zhengzhou 450001, Peoples R China.; Yu, B (corresponding author), Zhengzhou Univ, Minist Educ, Key Lab Adv Drug Preparat Technol, Zhengzhou 450001, Peoples R China.; Yu, B (corresponding author), China Pharmaceut Univ, State Key Lab Nat Med, Nanjing 210009, Peoples R China.

JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021; 14 (1):

Abstract

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme enzyme that catalyzes the oxidation of L-tryptophan. Functionally, IDO1 has played a pivotal role in ca......

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