Low-dose L-NAME induces salt sensitivity associated with sustained increased blood volume and sodium-chloride cotransporter activity in rodents

Wang, CH; Kawakami-Mori, F; Kang, L; Ayuzawa, N; Ogura, S; Koid, SS; Reheman, L; Yeerbolati, A; Liu, BB; Yatomi, Y; Chen, XM; Fujita, T; Shimosawa, T

Shimosawa, T (corresponding author), Int Univ Hlth & Welf, Sch Med, Dept Clin Lab, 852 Hatakeda, Chiba 2868520, Japan.

KIDNEY INTERNATIONAL, 2020; 98 (5): 1242

Abstract

To investigate the cause of salt sensitivity in a normotensive animal model, we treated rats with a low-dose of the nitric oxide synthase inhibitor, L......

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