LASP1 interacts with N-WASP to activate the Arp2/3 complex and facilitate colorectal cancer metastasis by increasing tumour budding and worsening the pattern of invasion

Yan, PP; Liu, J; Zhou, R; Lin, C; Wu, KH; Yang, SB; Yang, S; Zhou, JY; Xu, LJ; Wang, H; Zhao, L

Zhao, L (corresponding author), Southern Med Univ, Nanfang Hosp, Dept Pathol, Guangzhou, Peoples R China.; Zhao, L (corresponding author), Southern Med Univ, Sch Basic Med Sci, Dept Pathol, Guangzhou, Peoples R China.; Zhao, L (corresponding author), Southern Med Univ, Guangdong Prov Key Lab Mol Tumor Pathol, Guangzhou, Peoples R China.

ONCOGENE, 2020; 39 (35): 5743

Abstract

LIM and SH3 protein 1 (LASP1) is a metastasis-related protein reported to enhance tumour progression in colorectal cancer (CRC). However, the underlyi......

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