Beluga whale pVHL enhances HIF-2 alpha activity via inducing HIF-2 alpha proteasomal degradation under hypoxia

Bi, JL; Hu, B; Wang, J; Liu, X; Zheng, JS; Wang, D; Xiao, WH

Wang, D; Xiao, WH (reprint author), Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China.; Xiao, WH (reprint author), Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 43007

ONCOTARGET, 2017; 8 (26): 42272

Abstract

Aquatic mammals, such as cetaceans experience various depths, with accordingly diverse oxygenation, thus, cetaceans have developed adaptations for hyp......

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