Ascorbic Acid 2-Glucoside Stably Promotes the Primitiveness of Embryonic and Mesenchymal Stem Cells Through Ten-Eleven Translocation- and cAMP-Responsive Element-Binding Protein-1-Dependent Mechanisms

Lee, S; Lim, J; Lee, JH; Ju, H; Heo, J; Kim, Y; Kim, S; Yu, HY; Ryu, CM; Lee, SY; Han, JM; Oh, YM; Lee, H; Jang, H; Yoon, TJ; Ahn, HS; Kim, K; Kim, HR; Roe, JS; Chung, HM; Son, J; Kim, JS; Shin, DM

Son, J; Shin, DM (corresponding author), Univ Ulsan, Dept Biomed Sci, Asan Med Ctr, Coll Med, Pungnap 2 Dong, Seoul 05505, South Korea.; Kim, JS (corresponding author), Konkuk Univ, Sch Med, Dept Stem Cell Biol, Seoul 05029, South Korea.

ANTIOXIDANTS & REDOX SIGNALING, 2020; 32 (1): 35

Abstract

Aims: The naive or primitive states of stem cells (SCs) residing in specific niches are unstable and difficult to preserve in vitro. Vitamin C (VitC),......

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