Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function

Thomas, L; Xue, JX; Murali, SK; Fenton, RA; Rieg, JAD; Rieg, T

Rieg, T (reprint author), Univ S Florida, Dept Mol Pharmacol & Physiol, Morsani Coll Med, 12901 Bruce B Downs Blvd,MDC8, Tampa, FL 33612 USA.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2019; 30 (11): 2128

Abstract

Background The kidneys play an important role in phosphate homeostasis. Patients with CKD develop hyperphosphatemia in the later stages of the disease......

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