HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2

Cao, J; Sun, L; Aramsangtienchai, P; Spiegelman, NA; Zhang, XY; Huang, WS; Seto, E; Lin, HN

Lin, HN (reprint author), Cornell Univ, Dept Chem & Chem Biol, Ithaca, NY 14853 USA.; Lin, HN (reprint author), Cornell Univ, Howard Hughes Med Inst, Ithaca, NY 14853 USA.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (12): 5487

Abstract

The smallest histone deacetylase (HDAC) and the only class IV HDAC member, HDAC11, is reported to regulate immune activation and tumorigenesis, yet it......

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