Formation of an aminovinyl-cysteine residue in thioviridamides occurs through a path independent of known lanthionine synthetase activity

Qiu, YP; Liu, JY; Li, YQ; Xue, YQ; Liu, W

Liu, W (corresponding author), Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Ctr Excellence Mol Synth, State Key Lab Bioorgan & Nat Prod Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China.; Liu, W (corresponding author), Huzhou Ctr Biosynthet Innovat, 1366 Hongfeng Rd, Huzhou 313000, Peoples R China.

CELL CHEMICAL BIOLOGY, 2021; 28 (5): 675

Abstract

2-Aminovinyl-cysteine (AviCys) is a thioether amino acid shared by a variety of ribosomally synthesized and posttranslationally modified peptides (RiP......

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