TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

Zang, RC; Castro, MFG; McCune, BT; Zeng, QR; Rothlauf, PW; Sonnek, NM; Liu, ZM; Brulois, KF; Wang, X; Greenberg, HB; Diamond, MS; Ciorba, MA; Whelan, SPJ; Ding, SY

Ding, SY (corresponding author), Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA.

SCIENCE IMMUNOLOGY, 2020; 5 (47):

Abstract

Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19. However, it is unclear whether SARS-CoV-2 replicat......

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