Gut-resident CX3CR1(hi) macrophages induce tertiary lymphoid structures and IgA response in situ

Koscso, B; Kurapati, S; Rodrigues, RR; Nedjic, J; Gowda, K; Shin, C; Soni, C; Ashraf, AZ; Purushothaman, I; Palisoc, M; Xu, SL; Sun, HY; Chodisetti, SB; Lin, E; Mack, M; Kawasawa, YI; He, PN; Rahman, ZSM; Aifantis, I; Shulzhenko, N; Morgun, A; Bogunovic, M

Bogunovic, M (corresponding author), Univ Massachusetts, Med Sch, Dept Pathol, Worcester, MA 01605 USA.; Bogunovic, M (corresponding author), Penn State Univ, Coll Med, Dept Microbiol & Immunol, Hershey, PA USA.; Bogunovic, M (corresponding author), Milton S Hershey Med Ctr, Inflammatory Bowel Dis Ctr, Hershey, PA USA.

SCIENCE IMMUNOLOGY, 2020; 5 (46):

Abstract

Intestinal mononuclear phagocytes (MPs) are composed of heterogeneous dendritic cell (DC) and macrophage subsets necessary for the initiation of immun......

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