Optimized two-dimensional gel electrophoresis in an alkaline pH range improves the identification of intracellular CFDA-cisplatin-protein adducts in ovarian cancer cells

Kotz, S; Kullmann, M; Kalayda, GV; Dyballa-Rukes, N; Jaehde, U; Metzger, S

Metzger, S (reprint author), Univ Cologne, Cologne Bioctr, Zulpicherstr 47b, D-50674 Cologne, Germany.

ELECTROPHORESIS, 2018; 39 (12): 1488

Abstract

Intracellular binding of cisplatin to proteins has been associated with acquired resistance to chemotherapy. In our previous study we established an a......

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