Oncolytic Herpes Simplex Virus Type 2 Can Effectively Inhibit Colorectal Cancer Liver Metastasis by Modulating the Immune Status in the Tumor Microenvironment and Inducing Specific Antitumor Immunity

Zhang, W; Zeng, BB; Hu, X; Zou, LJ; Liang, J; Song, Y; Liu, BL; Liu, SM

Liu, SM (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Dept Pathol, Natl Canc Ctr,Canc Hosp, Beijing 100021, Peoples R China.; Liu, BL (corresponding author), Hubei Univ Technol, Natl Ctr Cellular Regulat & Mol Pharmaceut 111, Hubei Prov Cooperat Innovat Ctr Ind Fermentat, Key Lab Fermentat Engn,Minist Educ,Hubei Key Lab, Wuhan, Peoples R China.

HUMAN GENE THERAPY, 2021; 32 (3-4): 203

Abstract

Although colorectal cancer is the leading cause of death in patients with liver metastases, there are no efficient treatments available. Oncolytic vir......

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