Treatment of a Hemophilia B Mouse Model with Platelet-Targeted Expression of Factor IX Padua

Li, BB; Wu, ZH; Xu, WJ; Han, WW; Liu, JY; Wang, DW; Zhang, GW

Wang, DW (corresponding author), Shanghai Jiao Tong Univ, Natl Res Ctr Translat Med, Ruijin Hosp, Sch Med, 197 Rui Jin Rd II, Shanghai 200025, Peoples R China.; Zhang, GW (corresponding author), Hangzhou Normal Univ, Dept Basic Med Sci, Sch Med, 2318 Yuhangtang Rd, Hangzhou 311121, Zhejiang, Peoples R China.

HUMAN GENE THERAPY, 2021; 32 (9-10): 506

Abstract

Targeting the coagulation factor IX (FIX) expression in platelets has been shown to be effective in ameliorating bleeding in hemophilia B (HB) mice. T......

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