Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation

Matsuo, T; Isosaka, T; Hayashi, Y; Tang, LJ; Doi, A; Yasuda, A; Hayashi, M; Lee, CY; Cao, LQ; Kutsuna, N; Matsunaga, S; Matsuda, T; Yao, I; Setou, M; Kanagawa, D; Higasa, K; Ikawa, M; Liu, QH; Kobayakawa, R; Kobayakawa, K

Kobayakawa, R; Kobayakawa, K (corresponding author), Kansai Med Univ, Inst Biomed Sci, Dept Funct Neurosci, Osaka, Japan.; Liu, QH (corresponding author), Univ Tsukuba, Int Inst Integrat Sleep Med WPI IIIS, Tsukuba, Ibaraki, Japan.; Liu, QH (corresponding author), Natl Inst Biol Sci, Beijing, Peoples R China.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

Thiazoline-related innate fear-eliciting compounds (tFOs) orchestrate hypothermia, hypometabolism, and anti-hypoxia, which enable survival in lethal h......

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