酒精性肝病-话题@MedSci

#酒精性肝病#

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content=2019年被诊断为<a href='/topic/show?id=735a81364b7' target=_blank style='color:#2F92EE;'>#肝细胞癌#</a>的患者病因依次为<a href='/topic/show?id=a5452344016' target=_blank style='color:#2F92EE;'>#乙肝病毒#</a>感染（41.0%）、<a href='/topic/show?id=c28320934ab' target=_blank style='color:#2F92EE;'>#丙肝病毒#</a>感染（28.5%）、<a href='/topic/show?id=63ad95484f9' target=_blank style='color:#2F92EE;'>#酒精性肝病#</a>（18.4%）、<a href='/topic/show?id=266a10e378e5' target=_blank style='color:#2F92EE;'>#代谢相关脂肪性肝病#</a>（6.8%）、其他不太常见的危险因素（5.3%）。据预测，2020年至2040年间全球肝细胞癌新发病例数约增加55%，到2040年预计可诊断出140万肝细胞癌，且约有130人将死于肝细胞癌。一线治疗推荐方案为<a href='/topic/show?id=6bf49e844e9' target=_blank style='color:#2F92EE;'>#阿替利珠单抗#</a>联合<a href='/topic/show?id=0a9e922085f' target=_blank style='color:#2F92EE;'>#贝伐珠单抗#</a>。若患者存在胃食管和/或胃肠道出血高风险或其他贝伐珠单抗禁忌证，<a href='/topic/show?id=7b2910612398' target=_blank style='color:#2F92EE;'>#度伐利尤单抗#</a>+<a href='/topic/show?id=ba5c1e796cf' target=_blank 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href='/topic/show?id=63ad95484f9' target=_blank style='color:#2F92EE;'>#酒精性肝病#</a>, objectTitle=Gastroenterology：增强型肝纤维化测试、Fibrotest、弹性成像、间接肝纤维化指标等评估酒精性肝病患者进展性肝纤维化的效能, objectType=article, longId=126817, objectId=ad1a12681e0a, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=ad1a12681e0a, replyNumber=0, likeNumber=33, createdTime=2018-01-19, rootId=0, userName=446798725_87912765, userId=4f2c2500194, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=ad1a12681e0a, moduleTitle=Gastroenterology：增强型肝纤维化测试、Fibrotest、弹性成像、间接肝纤维化指标等评估酒精性肝病患者进展性肝纤维化的效能, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=ad1a12681e0a)], followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

2020-05-29

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#酒精性肝病# #肝脏硬度#

J Hepatol：使用肝脏硬度来预测和监测酒精相关肝病患者失代偿和死亡的风险

2024-03-09发表于上海

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全文收起 2019年被诊断为#肝细胞癌#的患者病因依次为#乙肝病毒#感染（41.0%）、#丙肝病毒#感染（28.5%）、#酒精性肝病#（18.4%）、#代谢相关脂肪性肝病#（6.8%）、其他不太常见的危险因素（5.3%）。据预测，2020年至2040年间全球肝细胞癌新发病例数约增加55%，到2040年预计可诊断出140万肝细胞癌，且约有130人将死于肝细胞癌。一线治疗推荐方案为#阿替利珠单抗#联合#贝伐珠单抗#。若患者存在胃食管和/或胃肠道出血高风险或其他贝伐珠单抗禁忌证，#度伐利尤单抗#+#Tremelimumab#可能是更合适的选择。对于存在使用免疫检查点抑制剂禁忌证的患者，如患有自身免疫性疾病或肝移植后接受免疫抑制剂治疗的患者，推荐一线治疗选择#仑伐替尼#或#索拉非尼#。

Nature子刊：全球超80万人死于肝癌！咖啡、阿司匹林、他汀、二甲双胍或可预防

2023-11-06发表于威斯康星

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#酒精性肝病#

Cell Discovery：上海交大贺明团队揭示酒精性肝病新机制及治疗新靶点

2021-10-22

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#酒精性肝病#

Hepatology: 果糖及其代谢产物升高会导致酒精性肝病的发生

2020-11-12

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#酒精性肝病#

J Hepatol: Maddrey评分<32分且病理提示存在脂肪性肝炎的酒精性肝病患者长期预后特点

2020-08-21

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#酒精性肝病#

2020 AISF临床实践指南：酒精性肝病

2020-02-11

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#酒精性肝病#

2019 SIA意见书：晚期酒精性肝病和重症急性酒精性肝炎的管理

2019-11-30

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#酒精性肝病#

酒精性肝病的预防和治疗指南（2018，中国）-英文版

2018-11-27

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#酒精性肝病#

世卫组织饮酒与健康报告发布，中国被严厉批评：酒精消费增幅76%，酒精性肝病比例翻倍，6%的男士死于饮酒

2018-09-26

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#酒精性肝病#

《2018年欧洲肝病学会临床实践指南：酒精性肝病管理》摘译

2018-07-14

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#酒精性肝病#

Hepatology：调节肠道胆汁酸/farnesoid X受体/成纤维细胞生长因子15轴，改善小鼠酒精性肝病

2018-06-30

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#酒精性肝病#

Liver Int：乙醇抑制了白细胞介素-37在酒精性肝病中发挥的抗炎作用

2018-06-26

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#酒精性肝病#

Eur J Gastroenterol Hepatol：患有非酒精性肝病的糖尿病患者，其心血管疾病的风险增加

2018-05-31

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#酒精性肝病#

Eur J Gastroenterol Hepatol：HA和M30，联合或单独使用，可能能够预测非酒精性肝病患者的显著肝纤维化

2018-05-31

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#酒精性肝病#

2018 EASL临床实践指南：酒精性肝病的管理

2018-04-15

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#酒精性肝病#

酒精性肝病防治指南（2018年更新版）

2018-04-14

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#酒精性肝病#

Hepatol Res：胰岛素耐受增加了非酒精性肝病患者2型糖尿病患病风险

2018-04-13

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#酒精性肝病#

《2018 年美国胃肠病学院酒精性肝病诊治临床指南》推荐意见

2018-04-04

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#酒精性肝病#

2018 ACG临床指南：酒精性肝病

2018-01-24

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#酒精性肝病#

Gastroenterology：增强型肝纤维化测试、Fibrotest、弹性成像、间接肝纤维化指标等评估酒精性肝病患者进展性肝纤维化的效能

2018-01-19

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