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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1998 2
2000 2
2002 1
2003 1
2004 3
2005 2
2007 1
2008 1
2009 1
2010 4
2011 3
2012 1
2013 5
2014 8
2015 5
2016 5
2017 3
2018 3
2019 3
2020 5
2021 3
2022 1
2023 2
2024 1

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63 results

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Page 1
When stem cells grow old: phenotypes and mechanisms of stem cell aging.
Schultz MB, Sinclair DA. Schultz MB, et al. Development. 2016 Jan 1;143(1):3-14. doi: 10.1242/dev.130633. Development. 2016. PMID: 26732838 Free PMC article. Review.
An attractive theory is that a loss in stem cell number and/or activity over time causes this decline. In accordance with this theory, aging phenotypes have been described for stem cells of multiple tissues, including those of the hematopoietic system, intestine, muscle, b …
An attractive theory is that a loss in stem cell number and/or activity over time causes this decline. In accordance with this theory, ag …
Conserved and novel functions of programmed cellular senescence during vertebrate development.
Davaapil H, Brockes JP, Yun MH. Davaapil H, et al. Development. 2017 Jan 1;144(1):106-114. doi: 10.1242/dev.138222. Epub 2016 Nov 25. Development. 2017. PMID: 27888193 Free PMC article.
Our findings uncover conserved and new roles of senescence in vertebrate organogenesis and support the view that cellular senescence may have arisen in evolution as a developmental mechanism....
Our findings uncover conserved and new roles of senescence in vertebrate organogenesis and support the view that cellular senescence may hav …
Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.
Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D. Cui CY, et al. Development. 2014 Oct;141(19):3752-60. doi: 10.1242/dev.109231. Development. 2014. PMID: 25249463 Free PMC article.
To maintain body temperature, sweat glands develop from embryonic ectoderm by a poorly defined mechanism. We demonstrate a temporal cascade of regulation during mouse sweat gland formation. ...
To maintain body temperature, sweat glands develop from embryonic ectoderm by a poorly defined mechanism. We demonstrate a temporal c …
Cell competition: the winners and losers of fitness selection.
Bowling S, Lawlor K, Rodríguez TA. Bowling S, et al. Development. 2019 Jul 5;146(13):dev167486. doi: 10.1242/dev.167486. Development. 2019. PMID: 31278123 Free article. Review.
The process has a myriad of positive roles in the organism: it selects against mutant cells in developing tissues, prevents the propagation of oncogenic cells and eliminates damaged cells during ageing. However, 'super-fit' cancer cells can exploit cell competition mech …
The process has a myriad of positive roles in the organism: it selects against mutant cells in developing tissues, prevents the propagation …
Tet family proteins and 5-hydroxymethylcytosine in development and disease.
Tan L, Shi YG. Tan L, et al. Development. 2012 Jun;139(11):1895-902. doi: 10.1242/dev.070771. Development. 2012. PMID: 22569552 Free PMC article. Review.
Over the past few decades, DNA methylation at the 5-position of cytosine (5-methylcytosine, 5mC) has emerged as an important epigenetic modification that plays essential roles in development, aging and disease. However, the mechanisms controlling 5mC dynamics remain …
Over the past few decades, DNA methylation at the 5-position of cytosine (5-methylcytosine, 5mC) has emerged as an important epigenetic modi …
Hox genes are crucial regulators of periosteal stem cell identity.
Leclerc K, Remark LH, Ramsukh M, Josephson AM, Palma L, Parente PEL, Sambon M, Lee S, Lopez EM, Morgani SM, Leucht P. Leclerc K, et al. Development. 2023 Mar 15;150(6):dev201391. doi: 10.1242/dev.201391. Epub 2023 Mar 24. Development. 2023. PMID: 36912250 Free PMC article.
Periosteal stem and progenitor cells (PSPCs) are major contributors to bone maintenance and repair. Deciphering the molecular mechanisms that regulate their function is crucial for the successful generation and application of future therapeutics. ...
Periosteal stem and progenitor cells (PSPCs) are major contributors to bone maintenance and repair. Deciphering the molecular mechanisms …
Intrinsic and extrinsic mechanisms regulating satellite cell function.
Dumont NA, Wang YX, Rudnicki MA. Dumont NA, et al. Development. 2015 May 1;142(9):1572-81. doi: 10.1242/dev.114223. Development. 2015. PMID: 25922523 Free PMC article. Review.
Thus, a complex balance between extrinsic cues and intrinsic regulatory mechanisms is needed to tightly control satellite cell cycle progression and cell fate determination. Defects in satellite cell regulation or in their niche, as observed in degenerative conditions such …
Thus, a complex balance between extrinsic cues and intrinsic regulatory mechanisms is needed to tightly control satellite cell cycle …
Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development.
Matsunaga E, Katahira T, Nakamura H. Matsunaga E, et al. Development. 2002 Nov;129(22):5269-77. doi: 10.1242/dev.129.22.5269. Development. 2002. PMID: 12399317
We have examined the relationship among isthmus related genes, and discuss the mechanism of the formation and maintenance of isthmic organizing activity....
We have examined the relationship among isthmus related genes, and discuss the mechanism of the formation and maintenance of isthmic …
Can injured adult CNS axons regenerate by recapitulating development?
Hilton BJ, Bradke F. Hilton BJ, et al. Development. 2017 Oct 1;144(19):3417-3429. doi: 10.1242/dev.148312. Development. 2017. PMID: 28974639 Review.
During development, by contrast, neurons extend axons effectively. A variety of intracellular mechanisms mediate this difference, including changes in gene expression, the ability to form a growth cone, differences in mitochondrial function/axonal transport and the efficac …
During development, by contrast, neurons extend axons effectively. A variety of intracellular mechanisms mediate this difference, inc …
63 results