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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1964 1
1965 1
1966 1
1968 4
1971 5
1972 2
1973 2
1974 2
1975 8
1976 11
1977 3
1978 15
1979 16
1980 15
1981 27
1982 45
1983 44
1984 46
1985 42
1986 48
1987 90
1988 136
1989 144
1990 172
1991 186
1992 206
1993 236
1994 274
1995 306
1996 312
1997 331
1998 419
1999 502
2000 582
2001 759
2002 953
2003 1161
2004 1380
2005 1580
2006 1708
2007 2023
2008 2286
2009 2543
2010 3130
2011 3725
2012 4242
2013 5513
2014 8596
2015 11199
2016 11241
2017 11423
2018 14730
2019 18070
2020 21751
2021 26623
2022 28242
2023 28471
2024 11515
2025 1

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202,619 results

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Page 1
The Frequency of Ras Mutations in Cancer.
Prior IA, Hood FE, Hartley JL. Prior IA, et al. Cancer Res. 2020 Jul 15;80(14):2969-2974. doi: 10.1158/0008-5472.CAN-19-3682. Epub 2020 Mar 24. Cancer Res. 2020. PMID: 32209560 Free PMC article. Review.
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation frequency of Ras, with quoted values varying from 10%-30%. This variability is at least in part due to the selective aggregation of data from d …
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation fre …
Emerging Role of CRISPR/Cas9 Technology for MicroRNAs Editing in Cancer Research.
Aquino-Jarquin G. Aquino-Jarquin G. Cancer Res. 2017 Dec 15;77(24):6812-6817. doi: 10.1158/0008-5472.CAN-17-2142. Epub 2017 Dec 5. Cancer Res. 2017. PMID: 29208606 Review.
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes of cancer pathogenesis. Because there are different miRNAs implicated in all the stages of cancer, for example, functioning a …
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes …
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
Sharbeen G, McCarroll JA, Akerman A, Kopecky C, Youkhana J, Kokkinos J, Holst J, Boyer C, Erkan M, Goldstein D, Timpson P, Cox TR, Pereira BA, Chitty JL, Fey SK, Najumudeen AK, Campbell AD, Sansom OJ, Ignacio RMC, Naim S, Liu J, Russia N, Lee J, Chou A, Johns A, Gill AJ, Gonzales-Aloy E, Gebski V, Guan YF, Pajic M, Turner N, Apte MV, Davis TP, Morton JP, Haghighi KS, Kasparian J, McLean BJ, Setargew YF, Phillips PA; Australian Pancreatic Cancer Genome Initiative. Sharbeen G, et al. Cancer Res. 2021 Jul 1;81(13):3461-3479. doi: 10.1158/0008-5472.CAN-20-2496. Epub 2021 May 12. Cancer Res. 2021. PMID: 33980655
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor signaling and the generation of fibrosis, the latter of which creates a physical barrier to drugs. ...
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor si …
Computational Radiomics System to Decode the Radiographic Phenotype.
van Griethuysen JJM, Fedorov A, Parmar C, Hosny A, Aucoin N, Narayan V, Beets-Tan RGH, Fillion-Robin JC, Pieper S, Aerts HJWL. van Griethuysen JJM, et al. Cancer Res. 2017 Nov 1;77(21):e104-e107. doi: 10.1158/0008-5472.CAN-17-0339. Cancer Res. 2017. PMID: 29092951 Free PMC article.
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intelligence (AI) technology, either based on engineered hard-coded algorithms or deep learning methods, can be used to develop noninvasive …
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intell …
M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer.
Lan J, Sun L, Xu F, Liu L, Hu F, Song D, Hou Z, Wu W, Luo X, Wang J, Yuan X, Hu J, Wang G. Lan J, et al. Cancer Res. 2019 Jan 1;79(1):146-158. doi: 10.1158/0008-5472.CAN-18-0014. Epub 2018 Nov 6. Cancer Res. 2019. PMID: 30401711
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, downregulating expression of BRG1, which has been identified as a key factor promoting the colorectal cancer metastasis, yet is downre …
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, d …
Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.
Voli F, Valli E, Lerra L, Kimpton K, Saletta F, Giorgi FM, Mercatelli D, Rouaen JRC, Shen S, Murray JE, Ahmed-Cox A, Cirillo G, Mayoh C, Beavis PA, Haber M, Trapani JA, Kavallaris M, Vittorio O. Voli F, et al. Cancer Res. 2020 Oct 1;80(19):4129-4144. doi: 10.1158/0008-5472.CAN-20-0471. Epub 2020 Aug 18. Cancer Res. 2020. PMID: 32816860
Here we show that intratumoral copper levels influence PD-L1 expression in cancer cells. Deep analysis of the The Cancer Genome Atlas database and tissue microarrays showed strong correlation between the major copper influx transporter copper transporter 1 (CTR-1) a …
Here we show that intratumoral copper levels influence PD-L1 expression in cancer cells. Deep analysis of the The Cancer Genom …
Quantification of Neoantigen-Mediated Immunoediting in Cancer Evolution.
Wu T, Wang G, Wang X, Wang S, Zhao X, Wu C, Ning W, Tao Z, Chen F, Liu XS. Wu T, et al. Cancer Res. 2022 Jun 15;82(12):2226-2238. doi: 10.1158/0008-5472.CAN-21-3717. Cancer Res. 2022. PMID: 35486454
Immunoediting includes three temporally distinct stages, termed elimination, equilibrium, and escape, and has been proposed to explain the interactions between cancer cells and the immune system during the evolution of cancer. However, the status of immunoediting in …
Immunoediting includes three temporally distinct stages, termed elimination, equilibrium, and escape, and has been proposed to explain the i …
A Dual PI3K/HDAC Inhibitor Induces Immunogenic Ferroptosis to Potentiate Cancer Immune Checkpoint Therapy.
Fan F, Liu P, Bao R, Chen J, Zhou M, Mo Z, Ma Y, Liu H, Zhou Y, Cai X, Qian C, Liu X. Fan F, et al. Cancer Res. 2021 Dec 15;81(24):6233-6245. doi: 10.1158/0008-5472.CAN-21-1547. Epub 2021 Oct 28. Cancer Res. 2021. PMID: 34711611
In this study, we developed a dual-targeting PI3K and HDAC inhibitor BEBT-908 that potently inhibits tumor cell growth and potentiates anti-PD1 therapy in mice by inducing immunogenic ferroptosis in cancer cells. Treatment with BEBT-908 promoted ferroptotic cell death of …
In this study, we developed a dual-targeting PI3K and HDAC inhibitor BEBT-908 that potently inhibits tumor cell growth and potentiates anti- …
Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database.
Camps J, Noël F, Liechti R, Massenet-Regad L, Rigade S, Götz L, Hoffmann C, Amblard E, Saichi M, Ibrahim MM, Pollard J, Medvedovic J, Roider HG, Soumelis V. Camps J, et al. Cancer Res. 2023 Feb 3;83(3):363-373. doi: 10.1158/0008-5472.CAN-22-0074. Cancer Res. 2023. PMID: 36459564 Free PMC article.
The development of single-cell RNA sequencing (scRNA-seq) technologies has greatly contributed to deciphering the tumor microenvironment (TME). ...We have developed IMMUcan scDB (https://immucanscdb.vital-it.ch), a fully integrated scRNA-seq database exclusively dedicated …
The development of single-cell RNA sequencing (scRNA-seq) technologies has greatly contributed to deciphering the tumor microenvironm …
Models in Translational Oncology: A Public Resource Database for Preclinical Cancer Research.
Galuschka C, Proynova R, Roth B, Augustin HG, Müller-Decker K. Galuschka C, et al. Cancer Res. 2017 May 15;77(10):2557-2563. doi: 10.1158/0008-5472.CAN-16-3099. Cancer Res. 2017. PMID: 28507049 Review.
The devastating diseases of human cancer are mimicked in basic and translational cancer research by a steadily increasing number of tumor models, a situation requiring a platform with standardized reports to share model data. ...Importantly, noneditable versi …
The devastating diseases of human cancer are mimicked in basic and translational cancer research by a steadily increasi …
202,619 results
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