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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1905 2
1907 1
1916 2
1917 1
1919 1
1920 2
1923 3
1924 3
1925 1
1926 2
1927 1
1928 4
1929 1
1931 3
1932 3
1933 6
1934 2
1935 5
1936 6
1937 1
1938 2
1939 1
1942 1
1943 2
1945 5
1946 19
1947 24
1948 29
1949 22
1950 22
1951 44
1952 47
1953 68
1954 75
1955 66
1956 73
1957 99
1958 112
1959 118
1960 157
1961 226
1962 249
1963 532
1964 742
1965 522
1966 612
1967 845
1968 996
1969 1121
1970 1181
1971 1397
1972 1673
1973 2023
1974 2835
1975 4262
1976 4842
1977 5068
1978 5785
1979 6930
1980 8239
1981 8915
1982 10182
1983 11325
1984 12594
1985 13810
1986 15039
1987 16236
1988 18076
1989 20656
1990 22624
1991 24004
1992 26224
1993 28271
1994 29958
1995 32218
1996 33517
1997 34650
1998 36725
1999 38388
2000 41599
2001 42953
2002 44709
2003 47611
2004 51700
2005 54711
2006 58099
2007 60719
2008 63212
2009 64617
2010 68816
2011 72934
2012 76830
2013 79574
2014 80239
2015 80002
2016 78533
2017 79366
2018 79814
2019 80707
2020 88596
2021 92494
2022 85018
2023 78377
2024 31920

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1,981,362 results

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Page 1
The Estrogen Receptors: An Overview from Different Perspectives.
Eyster KM. Eyster KM. Methods Mol Biol. 2016;1366:1-10. doi: 10.1007/978-1-4939-3127-9_1. Methods Mol Biol. 2016. PMID: 26585122 Review.
The estrogen receptors, ERalpha, ERbeta, and GPER, mediate the effects of estrogenic compounds on their target tissues. ...The purpose of this discussion of the estrogen receptors is to provide a brief overview of the estrogen receptors and estrogen action fr …
The estrogen receptors, ERalpha, ERbeta, and GPER, mediate the effects of estrogenic compounds on their target tissues. ...The purpos …
Leptin receptors.
Gorska E, Popko K, Stelmaszczyk-Emmel A, Ciepiela O, Kucharska A, Wasik M. Gorska E, et al. Eur J Med Res. 2010 Nov 4;15 Suppl 2(Suppl 2):50-4. doi: 10.1186/2047-783x-15-s2-50. Eur J Med Res. 2010. PMID: 21147620 Free PMC article. Review.
Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. According to its structural differences, the receptor's isoforms are divided into …
Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the pro …
Somatostatin receptors.
Lewin MJ. Lewin MJ. Scand J Gastroenterol Suppl. 1986;119:42-6. doi: 10.3109/00365528609087430. Scand J Gastroenterol Suppl. 1986. PMID: 2876505 Review.
More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from several approaches. The minimal active structure of the receptor(s) has been identified, and active minisomatostatins have be …
More insight into the biochemical structure and operation of the somatostatin receptor(s) has been gained in recent years from …
Muscarinic receptors: what we know.
Scarpero HM, Dmochowski RR. Scarpero HM, et al. Curr Urol Rep. 2003 Dec;4(6):421-8. doi: 10.1007/s11934-003-0021-3. Curr Urol Rep. 2003. PMID: 14622493 Review.
Alterations in the receptor's response to acetylcholine as a result of injury may lead to hypersensitivity and overactivity. The M(2) receptor subtype, which is mainly responsible for cardiac function, is the muscarinic receptor of highest proportion i …
Alterations in the receptor's response to acetylcholine as a result of injury may lead to hypersensitivity and overactivity. T …
Cell-surface receptors on macrophages and dendritic cells for attachment and entry of influenza virus.
Londrigan SL, Tate MD, Brooks AG, Reading PC. Londrigan SL, et al. J Leukoc Biol. 2012 Jul;92(1):97-106. doi: 10.1189/jlb.1011492. Epub 2011 Nov 28. J Leukoc Biol. 2012. PMID: 22124137 Free PMC article. Review.
Although it has been well established that cell-surface SA acts as a primary attachment receptor for IAV, the particular receptor(s) or coreceptor(s) that mediate IAV entry into any cell, including Mphi and DC, have not been clearly defined. ...Recent evidenc …
Although it has been well established that cell-surface SA acts as a primary attachment receptor for IAV, the particular receptor …
Allosteric modulators of G-protein-coupled receptors.
May LT, Christopoulos A. May LT, et al. Curr Opin Pharmacol. 2003 Oct;3(5):551-6. doi: 10.1016/s1471-4892(03)00107-3. Curr Opin Pharmacol. 2003. PMID: 14559102 Review.
Allosteric modulators of G-protein-coupled receptors (GPCRs) interact with binding sites on the receptor that are topographically distinct from the orthosteric site recognized by the receptor's endogenous agonist. Allosteric modulators offer several ad …
Allosteric modulators of G-protein-coupled receptors (GPCRs) interact with binding sites on the receptor that are topographica …
Allosteric modulation of G protein-coupled receptors.
May LT, Leach K, Sexton PM, Christopoulos A. May LT, et al. Annu Rev Pharmacol Toxicol. 2007;47:1-51. doi: 10.1146/annurev.pharmtox.47.120505.105159. Annu Rev Pharmacol Toxicol. 2007. PMID: 17009927 Review.
The past decade has witnessed a significant growth in the identification of allosteric modulators of G protein-coupled receptors (GPCRs), i.e., ligands that interact with binding sites that are topographically distinct from the orthosteric site recognized by the recepto …
The past decade has witnessed a significant growth in the identification of allosteric modulators of G protein-coupled receptors (GPC …
C1q-binding proteins and C1q receptors.
Nicholson-Weller A, Klickstein LB. Nicholson-Weller A, et al. Curr Opin Immunol. 1999 Feb;11(1):42-6. doi: 10.1016/s0952-7915(99)80008-9. Curr Opin Immunol. 1999. PMID: 10047536 Review.
C1q-induced cellular responses may be involved in host defense and in protection against autoimmunity because C1q-deficient humans have infectious complications and a very high incidence of autoimmune disease. The search for the C1q receptor(s), which has been ongoi …
C1q-induced cellular responses may be involved in host defense and in protection against autoimmunity because C1q-deficient humans have infe …
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus.
Yan H, Zhong G, Xu G, He W, Jing Z, Gao Z, Huang Y, Qi Y, Peng B, Wang H, Fu L, Song M, Chen P, Gao W, Ren B, Sun Y, Cai T, Feng X, Sui J, Li W. Yan H, et al. Elife. 2012 Nov 13;1:e00049. doi: 10.7554/eLife.00049. Elife. 2012. PMID: 23150796 Free PMC article.
The pre-S1 domain of the large envelope protein is a key determinant for receptor(s) binding. However, the identity of the receptor(s) is unknown. ...Moreover, replacing amino acids 157-165 of nonfunctional monkey NTCP with the human counterpart confer …
The pre-S1 domain of the large envelope protein is a key determinant for receptor(s) binding. However, the identity of the …
Allosteric Modulators of the Class A G Protein Coupled Receptors.
Tschammer N. Tschammer N. Adv Exp Med Biol. 2016;917:185-207. doi: 10.1007/978-3-319-32805-8_9. Adv Exp Med Biol. 2016. PMID: 27236557 Review.
The existence of ligands that allosterically modulate the G protein receptor (GPCR) functions provides both challenges and opportunities for drug development campaigns. ...In this review I discuss various aspects of allosteric modulation of GPCRs, which arise from the inte …
The existence of ligands that allosterically modulate the G protein receptor (GPCR) functions provides both challenges and opportunit …
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