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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 1
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2000 2
2001 1
2002 1
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2006 1
2008 1
2012 2
2014 1
2015 1
2016 1
2017 2
2018 1
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2020 1
2021 3
2022 4
2023 3
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30 results

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Page 1
WNT signaling in pre-granulosa cells is required for ovarian folliculogenesis and female fertility.
Habara O, Logan CY, Kanai-Azuma M, Nusse R, Takase HM. Habara O, et al. Development. 2021 May 1;148(9):dev198846. doi: 10.1242/dev.198846. Epub 2021 Apr 29. Development. 2021. PMID: 33914868 Free PMC article.
Precise control of primordial follicle activation (PFA) is essential for reproduction, but how this is achieved is unclear. Here, we show that canonical wingless-type MMTV integration site family (WNT) signaling is pivotal for pre-granulosa cell (pre-GC) activation during …
Precise control of primordial follicle activation (PFA) is essential for reproduction, but how this is achieved is unclear. Here, we …
Lysophosphatidic acid signalling in development.
Sheng X, Yung YC, Chen A, Chun J. Sheng X, et al. Development. 2015 Apr 15;142(8):1390-5. doi: 10.1242/dev.121723. Development. 2015. PMID: 25852197 Free PMC article. Review.
These LPA-influenced processes impact many aspects of organismal development. In particular, LPA signalling has been shown to affect fertility and reproduction, formation of the nervous system, and development of the vasculature. ...
These LPA-influenced processes impact many aspects of organismal development. In particular, LPA signalling has been shown to affect fert …
Reproductive genomics of the mouse: implications for human fertility and infertility.
Garretson A, Dumont BL, Handel MA. Garretson A, et al. Development. 2023 Feb 15;150(4):dev201313. doi: 10.1242/dev.201313. Epub 2023 Feb 13. Development. 2023. PMID: 36779988 Free PMC article.
As fertility is not a binary trait, attention is now appropriately focused on the oligogenic, quantitative aspects of reproduction. ...Finally, we discuss how what we know about the genomics of reproduction can ultimately be brought to the clinic, informing o …
As fertility is not a binary trait, attention is now appropriately focused on the oligogenic, quantitative aspects of reproduction …
A high-sugar diet, but not obesity, reduces female fertility in Drosophila melanogaster.
Nunes RD, Drummond-Barbosa D. Nunes RD, et al. Development. 2023 Oct 15;150(20):dev201769. doi: 10.1242/dev.201769. Epub 2023 Oct 16. Development. 2023. PMID: 37795747
Obesity is linked to reduced fertility in various species, from Drosophila to humans. Considering that obesity is often induced by changes in diet or eating behavior, it remains unclear whether obesity, diet, or both reduce fertility. ...These findings demonstrate t …
Obesity is linked to reduced fertility in various species, from Drosophila to humans. Considering that obesity is often induced by ch …
Casein kinase 1α regulates murine spermatogenesis via p53-Sox3 signaling.
Lu C, Zhang D, Zhang J, Li L, Qiu J, Gou K, Cui S. Lu C, et al. Development. 2022 Jul 1;149(13):dev200205. doi: 10.1242/dev.200205. Epub 2022 Jul 1. Development. 2022. PMID: 35698877
Collectively, our data suggest that CK1alpha regulates spermatogenesis and male fertility through p53-Sox3 signaling, and they deepen our understanding of the regulatory mechanism underlying the male reproductive system....
Collectively, our data suggest that CK1alpha regulates spermatogenesis and male fertility through p53-Sox3 signaling, and they deepen …
A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals.
Gerri C, McCarthy A, Mei Scott G, Regin M, Stamatiadis P, Brumm S, Simon CS, Lee J, Montesinos C, Hassitt C, Hockenhull S, Hampshire D, Elder K, Snell P, Christie L, Fouladi-Nashta AA, Van de Velde H, Niakan KK. Gerri C, et al. Development. 2023 Apr 15;150(8):dev201112. doi: 10.1242/dev.201112. Epub 2023 Apr 20. Development. 2023. PMID: 36971487 Free PMC article.
The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance.
Zhang H, Jiang JC, Wu YW, Yu YS, Wang HN, Ding NZ, Fan HY. Zhang H, et al. Development. 2022 Oct 1;149(19):dev200497. doi: 10.1242/dev.200497. Epub 2022 Oct 12. Development. 2022. PMID: 36178098
IR has been recognized as a key mechanism in the regulation of gene expression. However, the role of this mechanism in female reproduction in mammals remains unclear. RNA terminal phosphate cyclase B (RTCB) is a RNA ligase; we found that RTCB conditional knockout mice have …
IR has been recognized as a key mechanism in the regulation of gene expression. However, the role of this mechanism in female reproductio …
Arabidopsis microRNA167 controls patterns of ARF6 and ARF8 expression, and regulates both female and male reproduction.
Wu MF, Tian Q, Reed JW. Wu MF, et al. Development. 2006 Nov;133(21):4211-8. doi: 10.1242/dev.02602. Epub 2006 Oct 4. Development. 2006. PMID: 17021043
Thus, miR167 is essential for correct patterning of gene expression, and for fertility of both ovules and anthers. The essential patterning function of miR167 contrasts with cases from animals in which miRNAs reinforce or maintain transcriptionally established gene express …
Thus, miR167 is essential for correct patterning of gene expression, and for fertility of both ovules and anthers. The essential patt …
Loss of UBE2S causes meiosis I arrest with normal spindle assembly checkpoint dynamics in mouse oocytes.
Sun SM, Zhao BW, Li YY, Liu HY, Xu YH, Yang XM, Guo JN, Ouyang YC, Weng CJ, Guan YC, Sun QY, Wang ZB. Sun SM, et al. Development. 2024 Mar 15;151(6):dev202285. doi: 10.1242/dev.202285. Epub 2024 Mar 28. Development. 2024. PMID: 38546043
APC/C has been extensively studied, but the functions of UBE2S in oocyte maturation and mouse fertility are not clear. In this study, we used Ube2s knockout mice to explore the role of UBE2S in mouse oocytes. ...In conclusion, our findings reveal an indispensable regulator …
APC/C has been extensively studied, but the functions of UBE2S in oocyte maturation and mouse fertility are not clear. In this study, …
A transgenic system for targeted ablation of reproductive and maternal-effect genes.
Bertho S, Kaufman O, Lee K, Santos-Ledo A, Dellal D, Marlow FL. Bertho S, et al. Development. 2021 Jun 15;148(12):dev198010. doi: 10.1242/dev.198010. Epub 2021 Jun 18. Development. 2021. PMID: 34143203 Free PMC article.
Identifying these regulators is essential to fill the large gaps in our understanding of the mechanisms and molecular pathways contributing to fertility and to maternally regulated developmental processes. To identify these maternal factors, it is necessary to bypass the e …
Identifying these regulators is essential to fill the large gaps in our understanding of the mechanisms and molecular pathways contributing …
30 results