Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1987 1
1988 2
1989 3
1990 3
1991 1
1993 7
1994 6
1995 4
1996 5
1997 6
1998 5
1999 1
2000 11
2001 5
2002 9
2003 3
2004 10
2005 10
2006 14
2007 11
2008 13
2009 14
2010 8
2011 7
2012 13
2013 12
2014 19
2015 21
2016 20
2017 25
2018 14
2019 14
2020 19
2021 34
2022 22
2023 22
2024 11

Text availability

Article attribute

Article type

Publication date

Search Results

356 results

Results by year

Filters applied: . Clear all
Page 1
Mitochondrial fusion, fission, and mitochondrial toxicity.
Meyer JN, Leuthner TC, Luz AL. Meyer JN, et al. Toxicology. 2017 Nov 1;391:42-53. doi: 10.1016/j.tox.2017.07.019. Epub 2017 Aug 5. Toxicology. 2017. PMID: 28789970 Free PMC article. Review.
Mitochondrial dynamics vary based on developmental stage and age, cell type, environmental factors, and genetic background. Indeed, many mitochondrial homeostasis genes are human disease genes. ...Inhibition of mitochondrial dynamics also affects elimination of irreparable …
Mitochondrial dynamics vary based on developmental stage and age, cell type, environmental factors, and genetic background. Indeed, m …
A 3D microfluidic liver model for high throughput compound toxicity screening in the OrganoPlate®.
Bircsak KM, DeBiasio R, Miedel M, Alsebahi A, Reddinger R, Saleh A, Shun T, Vernetti LA, Gough A. Bircsak KM, et al. Toxicology. 2021 Feb 28;450:152667. doi: 10.1016/j.tox.2020.152667. Epub 2021 Jan 6. Toxicology. 2021. PMID: 33359578 Free article.
The model is comprised of aggregates of induced pluripotent stem cell (iPSC)-derived hepatocytes (iHep) seeded in an extracellular matrix in the organ channel and co-cultured with endothelial cells and THP-1 monoblasts differentiated to macrophages seeded in the vascular c …
The model is comprised of aggregates of induced pluripotent stem cell (iPSC)-derived hepatocytes (iHep) seeded in an extracellular ma …
Post-translational modification by SUMO.
Hannoun Z, Greenhough S, Jaffray E, Hay RT, Hay DC. Hannoun Z, et al. Toxicology. 2010 Dec 30;278(3):288-93. doi: 10.1016/j.tox.2010.07.013. Epub 2010 Jul 30. Toxicology. 2010. PMID: 20674646 Free article. Review.
Therefore, understanding the role of SUMOylation in cell biology may allow the development of more efficient models, important in streamlining the drug discovery process. This review will focus on protein SUMOylation and its role in stem cell and somatic c …
Therefore, understanding the role of SUMOylation in cell biology may allow the development of more efficient models, important …
Mechanisms of soft and hard electrophile toxicities.
LoPachin RM, Geohagen BC, Nordstroem LU. LoPachin RM, et al. Toxicology. 2019 Apr 15;418:62-69. doi: 10.1016/j.tox.2019.02.005. Epub 2019 Feb 28. Toxicology. 2019. PMID: 30826385 Free PMC article. Review.
Therefore, the purpose of this Review is to discuss electrophile-nucleophile chemistry as it pertains to cell injury and resulting organ toxicity. Our discussion will involve an introduction to the Hard and Soft, Acids and Bases (HSAB) theory of Pearson. ...The calculated …
Therefore, the purpose of this Review is to discuss electrophile-nucleophile chemistry as it pertains to cell injury and resulting or …
Toxicity mechanism of acrolein on DNA damage and apoptosis in BEAS-2B cells: Insights from cell biology and molecular docking analyses.
Liu D, Cheng Y, Tang Z, Mei X, Cao X, Liu J. Liu D, et al. Toxicology. 2022 Jan 30;466:153083. doi: 10.1016/j.tox.2021.153083. Epub 2021 Dec 24. Toxicology. 2022. PMID: 34958888
The molecular mechanism was investigated base on DNA damage and mitochondrial apoptosis pathways. The results showed that after exposure to acrolein, the cell viability, glutathione (GSH) of BEAS-2B cells were reduced. Reactive oxygen species (ROS) level significantly incr …
The molecular mechanism was investigated base on DNA damage and mitochondrial apoptosis pathways. The results showed that after exposure to …
Aminoglycoside induced ototoxicity.
Guthrie OW. Guthrie OW. Toxicology. 2008 Jul 30;249(2-3):91-6. doi: 10.1016/j.tox.2008.04.015. Epub 2008 Apr 29. Toxicology. 2008. PMID: 18514377 Review.
The use of high-throughput screening techniques to evaluate mitochondrial toxicity.
Wills LP. Wills LP. Toxicology. 2017 Nov 1;391:34-41. doi: 10.1016/j.tox.2017.07.020. Epub 2017 Aug 5. Toxicology. 2017. PMID: 28789971 Review.
Mitochondrial toxicants are compounds that cause a decrease in the number of mitochondria within a cell, and/or decrease the ability of mitochondria to perform normal functions including producing adenosine triphosphate (ATP) and maintaining cellular homeostasis. ...
Mitochondrial toxicants are compounds that cause a decrease in the number of mitochondria within a cell, and/or decrease the ability …
Cytotoxicity and mechanism of action of metal complexes: An overview.
Abdolmaleki S, Khaksar S, Aliabadi A, Panjehpour A, Motieiyan E, Marabello D, Faraji MH, Beihaghi M. Abdolmaleki S, et al. Toxicology. 2023 Jun 15;492:153516. doi: 10.1016/j.tox.2023.153516. Epub 2023 Apr 20. Toxicology. 2023. PMID: 37087063 Review.
Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival.
Rose J, Brian C, Woods J, Pappa A, Panayiotidis MI, Powers R, Franco R. Rose J, et al. Toxicology. 2017 Nov 1;391:109-115. doi: 10.1016/j.tox.2017.06.011. Epub 2017 Jun 26. Toxicology. 2017. PMID: 28655545 Free PMC article. Review.
Neurons rely on oxidative phosphorylation to meet their energy requirements and thus alterations in mitochondrial function are linked to energy failure and neuronal cell death. Furthermore, in neurons, dysfunctional mitochondria are reported to increase the steady-state le …
Neurons rely on oxidative phosphorylation to meet their energy requirements and thus alterations in mitochondrial function are linked to ene …
356 results