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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 2
1953 2
1954 1
1955 1
1956 1
1957 1
1958 1
1961 1
1962 1
1963 5
1964 9
1965 11
1966 16
1967 29
1968 53
1969 69
1970 87
1971 158
1972 142
1973 161
1974 202
1975 292
1976 305
1977 319
1978 425
1979 467
1980 563
1981 623
1982 718
1983 990
1984 1258
1985 1449
1986 1645
1987 2091
1988 2654
1989 2968
1990 3375
1991 3610
1992 4112
1993 4551
1994 5119
1995 5501
1996 5740
1997 6212
1998 6214
1999 6746
2000 7865
2001 7942
2002 8138
2003 8838
2004 9406
2005 9827
2006 10161
2007 10567
2008 10965
2009 11319
2010 12399
2011 13521
2012 14441
2013 15428
2014 18196
2015 19875
2016 20664
2017 21378
2018 22107
2019 24229
2020 27210
2021 30017
2022 28452
2023 26168
2024 9370

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427,839 results

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Page 1
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
Horak P, Griffith M, Danos AM, Pitel BA, Madhavan S, Liu X, Chow C, Williams H, Carmody L, Barrow-Laing L, Rieke D, Kreutzfeldt S, Stenzinger A, Tamborero D, Benary M, Rajagopal PS, Ida CM, Lesmana H, Satgunaseelan L, Merker JD, Tolstorukov MY, Campregher PV, Warner JL, Rao S, Natesan M, Shen H, Venstrom J, Roy S, Tao K, Kanagal-Shamanna R, Xu X, Ritter DI, Pagel K, Krysiak K, Dubuc A, Akkari YM, Li XS, Lee J, King I, Raca G, Wagner AH, Li MM, Plon SE, Kulkarni S, Griffith OL, Chakravarty D, Sonkin D. Horak P, et al. Genet Med. 2022 May;24(5):986-998. doi: 10.1016/j.gim.2022.01.001. Epub 2022 Jan 29. Genet Med. 2022. PMID: 35101336 Free PMC article.
This insufficient guidance leads to inconsistent classification of rare somatic variants in cancer, generates variability in their clinical interpretation, and, importantly, affects patient care. Therefore, it is essential to address this unmet need. METHODS: Clinical G …
This insufficient guidance leads to inconsistent classification of rare somatic variants in cancer, generates variability in their cl …
The emerging clinical relevance of genomics in cancer medicine.
Berger MF, Mardis ER. Berger MF, et al. Nat Rev Clin Oncol. 2018 Jun;15(6):353-365. doi: 10.1038/s41571-018-0002-6. Nat Rev Clin Oncol. 2018. PMID: 29599476 Free PMC article. Review.
The combination of next-generation sequencing and advanced computational data analysis approaches has revolutionized our understanding of the genomic underpinnings of cancer development and progression. The coincident development of targeted small molecule and antib …
The combination of next-generation sequencing and advanced computational data analysis approaches has revolutionized our understanding of th …
Applications of Support Vector Machine (SVM) Learning in Cancer Genomics.
Huang S, Cai N, Pacheco PP, Narrandes S, Wang Y, Xu W. Huang S, et al. Cancer Genomics Proteomics. 2018 Jan-Feb;15(1):41-51. doi: 10.21873/cgp.20063. Cancer Genomics Proteomics. 2018. PMID: 29275361 Free PMC article. Review.
Machine learning with maximization (support) of separating margin (vector), called support vector machine (SVM) learning, is a powerful classification tool that has been used for cancer genomic classification or subtyping. Today, as advancements in high-throughput t …
Machine learning with maximization (support) of separating margin (vector), called support vector machine (SVM) learning, is a powerful clas …
Genomics and cancer.
Onyango P. Onyango P. Curr Opin Oncol. 2002 Jan;14(1):79-85. doi: 10.1097/00001622-200201000-00014. Curr Opin Oncol. 2002. PMID: 11790985 Review.
Genetic and environmental factors are responsible for the genomic lesions that cause cancer, a complex genetic disease associated with genomic instability. Studies aimed at deciphering the lesions in cancer have focused mainly on one or a few genes, de …
Genetic and environmental factors are responsible for the genomic lesions that cause cancer, a complex genetic disease associa …
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
Yang W, Soares J, Greninger P, Edelman EJ, Lightfoot H, Forbes S, Bindal N, Beare D, Smith JA, Thompson IR, Ramaswamy S, Futreal PA, Haber DA, Stratton MR, Benes C, McDermott U, Garnett MJ. Yang W, et al. Nucleic Acids Res. 2013 Jan;41(Database issue):D955-61. doi: 10.1093/nar/gks1111. Epub 2012 Nov 23. Nucleic Acids Res. 2013. PMID: 23180760 Free PMC article.
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public …
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers f …
The cancer genome.
Stratton MR, Campbell PJ, Futreal PA. Stratton MR, et al. Nature. 2009 Apr 9;458(7239):719-24. doi: 10.1038/nature07943. Nature. 2009. PMID: 19360079 Free PMC article. Review.
All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over the past quarter of a century much has been learnt about these mutations and the abnormal genes that operate in human cancers. We are n …
All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over th …
Functional genomics of complex cancer genomes.
Menghi F, Liu ET. Menghi F, et al. Nat Commun. 2022 Oct 7;13(1):5908. doi: 10.1038/s41467-022-33717-8. Nat Commun. 2022. PMID: 36207330 Free PMC article.
Cancer functional genomics is the study of how genetic, epigenetic, and transcriptional alterations affect cancer phenotypes, such as growth and therapeutic response. Here, we comment on how, taking advantage of next generation sequencing, functional genom …
Cancer functional genomics is the study of how genetic, epigenetic, and transcriptional alterations affect cancer pheno …
Structural variations in cancer and the 3D genome.
Dubois F, Sidiropoulos N, Weischenfeldt J, Beroukhim R. Dubois F, et al. Nat Rev Cancer. 2022 Sep;22(9):533-546. doi: 10.1038/s41568-022-00488-9. Epub 2022 Jun 28. Nat Rev Cancer. 2022. PMID: 35764888 Free PMC article. Review.
Recently, analyses of large whole-genome sequencing data sets revealed features that impact rates of SVs across the genome in different cancers. ...This Perspective discusses how the folding of the 3D genome, and differences in its folding across cell …
Recently, analyses of large whole-genome sequencing data sets revealed features that impact rates of SVs across the genome in …
Cancer genomics and pathology: all together now.
Shibata T. Shibata T. Pathol Int. 2012 Oct;62(10):647-59. doi: 10.1111/j.1440-1827.2012.02855.x. Pathol Int. 2012. PMID: 23005591 Review.
Cancer develops from a single cell with stepwise accumulation of genomic alterations. Recent innovative sequencing technologies have made it possible to sequence the full cancer genome. Cancer genome sequencing has been productive and hel …
Cancer develops from a single cell with stepwise accumulation of genomic alterations. Recent innovative sequencing technologie …
Epstein-Barr virus strain variation and cancer.
Kanda T, Yajima M, Ikuta K. Kanda T, et al. Cancer Sci. 2019 Apr;110(4):1132-1139. doi: 10.1111/cas.13954. Epub 2019 Feb 21. Cancer Sci. 2019. PMID: 30697862 Free PMC article. Review.
Recent advances in deep sequencing technology enabled high-throughput sequencing of the EBV genome from clinical samples. Rapid cloning and sequencing of cancer-derived EBV genomes, followed by reconstitution of infectious virus, have also become possible. Th …
Recent advances in deep sequencing technology enabled high-throughput sequencing of the EBV genome from clinical samples. Rapid cloni …
427,839 results
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