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Dicistrovirus-Host Molecular Interactions.
Warsaba R, Sadasivan J, Jan E. Warsaba R, et al. Curr Issues Mol Biol. 2020;34:83-112. doi: 10.21775/cimb.034.083. Epub 2019 Jun 6. Curr Issues Mol Biol. 2020. PMID: 31167957 Free article.
In this chapter, we provide an overview of current and past research on dicistroviruses including the viral life cycle, viral translational control mechanisms, virus structure, and the use of dicistrovirus infection in Drosophila as a model to identify insect antiviral res …
In this chapter, we provide an overview of current and past research on dicistroviruses including the viral life cycle, viral translational …
A Critical Review of the Concept of Transgenic Plants: Insights into Pharmaceutical Biotechnology and Molecular Farming.
Abiri R, Valdiani A, Maziah M, Shaharuddin NA, Sahebi M, Yusof ZN, Atabaki N, Talei D. Abiri R, et al. Curr Issues Mol Biol. 2016;18:21-42. Epub 2015 May 6. Curr Issues Mol Biol. 2016. PMID: 25944541 Free article. Review.
Using transgenic plants for the production of high-value recombinant proteins for industrial and clinical applications has become a promising alternative to using conventional bioproduction systems, such as bacteria, yeast, and cultured insect and animal cells. This novel …
Using transgenic plants for the production of high-value recombinant proteins for industrial and clinical applications has become a promisin …
Advances in Tetravirus Research: New Insight Into the Infectious Virus Lifecycle and an Expanding Host Range.
Dorrington RA, Jiwaji M, Awando JA, Bruyn MM. Dorrington RA, et al. Curr Issues Mol Biol. 2020;34:145-162. doi: 10.21775/cimb.034.145. Epub 2019 Jun 6. Curr Issues Mol Biol. 2020. PMID: 31167959 Free article. Review.
Tetraviruses are classified into three families, the Alphatetraviridae, Permutotetraviridae and Carmotetraviridae, according to the divergent characteristics of their respective viral replicases. Tetraviruses generally infect the larvae of lepidopteran insect species, many …
Tetraviruses are classified into three families, the Alphatetraviridae, Permutotetraviridae and Carmotetraviridae, according to the divergen …
Looking Through the Lens of 'Omics Technologies: Insights Into the Transmission of Insect Vector-borne Plant Viruses.
Wilson JR, DeBlasio SL, Alexander MM, Heck M. Wilson JR, et al. Curr Issues Mol Biol. 2020;34:113-144. doi: 10.21775/cimb.034.113. Epub 2019 Jun 6. Curr Issues Mol Biol. 2020. PMID: 31167958 Free article.
Plant viruses transmitted by these insects target similar tissues, genes, and proteins within the insect to facilitate plant-to-plant transmission with some degree of specificity at the molecular level. 'Omics experiments are becoming increasingly important and practical f …
Plant viruses transmitted by these insects target similar tissues, genes, and proteins within the insect to facilitate plant-to-plant …
Exploration of carbohydrate binding behavior and anti-proliferative activities of Arisaema tortuosum lectin.
Thakur K, Kaur T, Kaur M, Hora R, Singh J. Thakur K, et al. BMC Mol Biol. 2019 May 7;20(1):15. doi: 10.1186/s12867-019-0132-0. BMC Mol Biol. 2019. PMID: 31064325 Free PMC article.
Through their specific binding property, they have proven to be anti-cancer, anti-insect, anti-viral agents without affecting the non-target cells. The Arisaema tortuosum lectin (ATL) is a known anti-insect and anti-cancer candidate, also has interesting physical pr …
Through their specific binding property, they have proven to be anti-cancer, anti-insect, anti-viral agents without affecting the non …
Molecular analysis of Ku redox regulation.
Bennett SM, Neher TM, Shatilla A, Turchi JJ. Bennett SM, et al. BMC Mol Biol. 2009 Aug 28;10:86. doi: 10.1186/1471-2199-10-86. BMC Mol Biol. 2009. PMID: 19715578 Free PMC article.
RESULTS: We effectively removed the C-terminal domain of Ku80 generating a truncation mutant and co-expressed this variant with wild type Ku70 in an insect cell system to create a Ku70/80DeltaC heterodimer. We also generated two single amino acid variants of Cys493, replac …
RESULTS: We effectively removed the C-terminal domain of Ku80 generating a truncation mutant and co-expressed this variant with wild type Ku …
Rhythmic expression of the cycle gene in a hematophagous insect vector.
Meireles-Filho AC, Amoretty PR, Souza NA, Kyriacou CP, Peixoto AA. Meireles-Filho AC, et al. BMC Mol Biol. 2006 Oct 27;7:38. doi: 10.1186/1471-2199-7-38. BMC Mol Biol. 2006. PMID: 17069657 Free PMC article.
In this mechanism the cycle (or bmal1) gene, which is constitutively expressed, plays a critical role activating the expression of genes that will later inhibit their own activity, thereby closing the loop. Unlike Drosophila, the molecular clock of insect vectors is poorly …
In this mechanism the cycle (or bmal1) gene, which is constitutively expressed, plays a critical role activating the expression of genes tha …