Brit J Cancer:夜班工作与乳腺癌风险

2019-05-31 xing.T 网络

由此可见,该研究的数据,缺乏整体相关性,并且与剂量、持续时间和强度之间的所有测量值无关,所以并不支持女性夜班工作增加患乳腺癌的风险。

夜班工作可能会影响乳腺癌风险,可能是褪黑激素抑制或昼夜节律紊乱所致,但流行病学证据尚无定论。

近日,肿瘤领域权威杂志British Journal of Cancer上发表了一篇研究文章,研究人员使用来自Generations Study队列的系列调查问卷,并根据潜在的混杂因素进行了调整后,估计了与过去10年内的夜班工作者相关的乳腺癌危险比(HR)和95%置信区间(95%CI)。

在2003-2014年期间招募的102869名女性中,中位随访9.5年,2059名女性发展为浸润性乳腺癌。与夜班工作相关的HR为1.00(95%CI为0.86-1.15)。平均每周夜班工作量所致的风险呈显著增加趋势(P=0.035),但每周工作小时数、每周工作夜数、每周平均工作时数、累积工作年数、累积工时、停工时间、职业类型、开始夜班工作的年龄、或首次怀孕年龄并未明显增加乳腺癌风险。

由此可见,该研究的数据,缺乏整体相关性,并且与剂量、持续时间和强度之间的所有测量值无关,所以并不支持女性夜班工作增加患乳腺癌的风险。 

原始出处:

Michael E. Jones.et al.Night shift work and risk of breast cancer in women: the Generations Study cohort.British Journal of Cancer.2019.https://www.nature.com/articles/s41416-019-0485-7

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=975813, encodeId=db2d9e5813f1, content=<a href='/topic/show?id=4ab143518a3' target=_blank style='color:#2F92EE;'>#夜班#</a>护理人员会不会更严重?, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43518, encryptionId=4ab143518a3, topicName=夜班)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Tue Jun 22 14:34:24 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085294, encodeId=c051208529456, content=<a href='/topic/show?id=3447435204a' target=_blank style='color:#2F92EE;'>#夜班工作#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43520, encryptionId=3447435204a, topicName=夜班工作)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Mon Jun 03 05:30:00 CST 2019, time=2019-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770318, encodeId=ba1f1e7031870, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Sat Jan 18 10:30:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061850, encodeId=a7b12061850a9, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Aug 28 00:30:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=367118, encodeId=5b7436e118ac, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/8535b99e11f8425ea0d00535473afd64/2d2121d6fde646e4b4ea8d46ebb52b92.jpg, createdBy=e2423643634, createdName=133d9d3cm85暂无昵称, createdTime=Sat Jun 01 15:40:22 CST 2019, time=2019-06-01, status=1, ipAttribution=)]
    2021-06-22 小小医者

    #夜班#护理人员会不会更严重?

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=975813, encodeId=db2d9e5813f1, content=<a href='/topic/show?id=4ab143518a3' target=_blank style='color:#2F92EE;'>#夜班#</a>护理人员会不会更严重?, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43518, encryptionId=4ab143518a3, topicName=夜班)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Tue Jun 22 14:34:24 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085294, encodeId=c051208529456, content=<a href='/topic/show?id=3447435204a' target=_blank style='color:#2F92EE;'>#夜班工作#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43520, encryptionId=3447435204a, topicName=夜班工作)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Mon Jun 03 05:30:00 CST 2019, time=2019-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770318, encodeId=ba1f1e7031870, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Sat Jan 18 10:30:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061850, encodeId=a7b12061850a9, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Aug 28 00:30:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=367118, encodeId=5b7436e118ac, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/8535b99e11f8425ea0d00535473afd64/2d2121d6fde646e4b4ea8d46ebb52b92.jpg, createdBy=e2423643634, createdName=133d9d3cm85暂无昵称, createdTime=Sat Jun 01 15:40:22 CST 2019, time=2019-06-01, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=975813, encodeId=db2d9e5813f1, content=<a href='/topic/show?id=4ab143518a3' target=_blank style='color:#2F92EE;'>#夜班#</a>护理人员会不会更严重?, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43518, encryptionId=4ab143518a3, topicName=夜班)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Tue Jun 22 14:34:24 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085294, encodeId=c051208529456, content=<a href='/topic/show?id=3447435204a' target=_blank style='color:#2F92EE;'>#夜班工作#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43520, encryptionId=3447435204a, topicName=夜班工作)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Mon Jun 03 05:30:00 CST 2019, time=2019-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770318, encodeId=ba1f1e7031870, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Sat Jan 18 10:30:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061850, encodeId=a7b12061850a9, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Aug 28 00:30:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=367118, encodeId=5b7436e118ac, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/8535b99e11f8425ea0d00535473afd64/2d2121d6fde646e4b4ea8d46ebb52b92.jpg, createdBy=e2423643634, createdName=133d9d3cm85暂无昵称, createdTime=Sat Jun 01 15:40:22 CST 2019, time=2019-06-01, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=975813, encodeId=db2d9e5813f1, content=<a href='/topic/show?id=4ab143518a3' target=_blank style='color:#2F92EE;'>#夜班#</a>护理人员会不会更严重?, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43518, encryptionId=4ab143518a3, topicName=夜班)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Tue Jun 22 14:34:24 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085294, encodeId=c051208529456, content=<a href='/topic/show?id=3447435204a' target=_blank style='color:#2F92EE;'>#夜班工作#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43520, encryptionId=3447435204a, topicName=夜班工作)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Mon Jun 03 05:30:00 CST 2019, time=2019-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770318, encodeId=ba1f1e7031870, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Sat Jan 18 10:30:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061850, encodeId=a7b12061850a9, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Aug 28 00:30:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=367118, encodeId=5b7436e118ac, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/8535b99e11f8425ea0d00535473afd64/2d2121d6fde646e4b4ea8d46ebb52b92.jpg, createdBy=e2423643634, createdName=133d9d3cm85暂无昵称, createdTime=Sat Jun 01 15:40:22 CST 2019, time=2019-06-01, status=1, ipAttribution=)]
    2019-08-28 sjq027
  5. [GetPortalCommentsPageByObjectIdResponse(id=975813, encodeId=db2d9e5813f1, content=<a href='/topic/show?id=4ab143518a3' target=_blank style='color:#2F92EE;'>#夜班#</a>护理人员会不会更严重?, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43518, encryptionId=4ab143518a3, topicName=夜班)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Tue Jun 22 14:34:24 CST 2021, time=2021-06-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2085294, encodeId=c051208529456, content=<a href='/topic/show?id=3447435204a' target=_blank style='color:#2F92EE;'>#夜班工作#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=43520, encryptionId=3447435204a, topicName=夜班工作)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Mon Jun 03 05:30:00 CST 2019, time=2019-06-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770318, encodeId=ba1f1e7031870, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Sat Jan 18 10:30:00 CST 2020, time=2020-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061850, encodeId=a7b12061850a9, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Wed Aug 28 00:30:00 CST 2019, time=2019-08-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=367118, encodeId=5b7436e118ac, content=学习了,谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210319/8535b99e11f8425ea0d00535473afd64/2d2121d6fde646e4b4ea8d46ebb52b92.jpg, createdBy=e2423643634, createdName=133d9d3cm85暂无昵称, createdTime=Sat Jun 01 15:40:22 CST 2019, time=2019-06-01, status=1, ipAttribution=)]
    2019-06-01 133d9d3cm85暂无昵称

    学习了,谢谢

    0