Circulation:年轻人群心脏性猝死的危险因素有哪些

2018-01-04 国际循环编辑部 国际循环

年轻人群心搏骤停(SCA)预防是尚未得到解决的公共卫生问题,体力活动是SCA的已知触发因素之一。

年轻人群心搏骤停(SCA)预防是尚未得到解决的公共卫生问题,体力活动是SCA的已知触发因素之一。尽管年轻时期标准心血管危险因素的存在与后续成年期的发病率及病死率具有相关性,但上述危险因素对于年轻人群SCA的潜在贡献尚不清楚。Circulation发表的一项最新前瞻性研究就可导致年轻人群SCA的危险因素进行探讨。

研究者Cedars-Sinai医学中心的Jayaraman R等,对2002~2015年美国俄勒冈州波特兰地区3775例SCA患者中186例(5%)5~34岁的年轻患者[平均年龄为(25.9±6.8)岁,男性为67%]进行分析,评估标准心血管危险因素与SCA的相关性。

结果发现,年轻SCA患者中,仅29%在SCA前存在预警征,其中26例(14%)患者由运动触发,160例为非运动因素触发。进一步分析发现,年龄≤18岁、19~25岁及25~34岁人群中,运动相关SCA的比例分别为39%、13%和7%。与非运动相关SCA相比,运动相关SCA患者更多存在可电击性心律,SCA后生存率更高(28%vs.11%,P=0.05)。总之,分析显示,与SCA相关的最常见因素依次是致心律失常性猝死综合征(31%)、冠状动脉疾病(22%)、肥厚型心肌病(14%)。另外,SCA患者中已知心血管危险因素(肥胖、糖尿病高血压、高脂血症及吸烟)患病率较高,其中58%的SCA患者合并至少一种上述危险因素。

综上可见,运动仅是少数SCA患者的触发因素,大多数SCA患者猝死前并无预警症状。此外,超半数SCA患者存在标准已知心血管危险因素。这提示,未来有必要采取公共卫生学方法针对年轻人群进行心血管危险因素的早期筛查

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    2018-01-04 1e127dd4m40(暂无匿称)

    学习了

    0

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    2018-01-04 方舒

    学习

    0

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    2018-01-04 131****2916

    不错的文章值得推荐

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2060625, encodeId=41cb206062533, content=<a href='/topic/show?id=a8984896926' target=_blank style='color:#2F92EE;'>#年轻人群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=48969, encryptionId=a8984896926, topicName=年轻人群)], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=47c5349, createdName=tastas, createdTime=Fri Sep 21 17:05:00 CST 2018, time=2018-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598975, encodeId=2d4b15989e573, content=<a href='/topic/show?id=862b51508e2' target=_blank style='color:#2F92EE;'>#心脏性猝死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51508, encryptionId=862b51508e2, topicName=心脏性猝死)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=aede18658739, createdName=ewsr7, createdTime=Sat Jan 06 12:05:00 CST 2018, time=2018-01-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275512, encodeId=cc032e551210, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo4cyIbibqa2VuNGCKeyRxITYNqLTIaoFo3Jx2LSawp8yrFSs1CIXKv1jyXV97ecnxhhktGKkPP9onfJFZCbiayLgic/0, createdBy=3f1c1956638, createdName=1e127dd4m40(暂无匿称), createdTime=Thu Jan 04 23:16:08 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275506, encodeId=98c12e5506a3, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Thu Jan 04 22:41:37 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275504, encodeId=97432e5504c0, content=不错的文章值得推荐, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04f22055142, createdName=131****2916, createdTime=Thu Jan 04 22:36:03 CST 2018, time=2018-01-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=275500, encodeId=c1332e550082, content=学习了.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Thu Jan 04 22:24:44 CST 2018, time=2018-01-04, status=1, ipAttribution=)]
    2018-01-04 天地飞扬

    学习了.谢谢分享!

    0

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