免疫系统与生物材料：不是敌人而是盟友

2016-04-26 科学公园科学公园

各种各样的生物材料经常被植入人体以治疗疾病或者修复机体损伤。在设计和加工这些生物材料时，一个主要的原则是设法降低这些材料在植入体内后对免疫系统的刺激，然而一项新的研究却表明：适当的免疫系统反应反而有助于生物材料更好地发挥作用。来自美国约翰·霍普金斯大学的研究人员首先在普通的实验用小鼠身上制造肌肉损伤，然后分别将几种生物材料植入受伤部位。观察表明，植入的生物材料显著地刺激了受伤部位周围的免

各种各样的生物材料经常被植入人体以治疗疾病或者修复机体损伤。在设计和加工这些生物材料时，一个主要的原则是设法降低这些材料在植入体内后对免疫系统的刺激，然而一项新的研究却表明：适当的免疫系统反应反而有助于生物材料更好地发挥作用。

来自美国约翰·霍普金斯大学的研究人员首先在普通的实验用小鼠身上制造肌肉损伤，然后分别将几种生物材料植入受伤部位。观察表明，植入的生物材料显著地刺激了受伤部位周围的免疫系统反应。接下来他们又在另一种经过基因工程改造的小鼠身上重复实验，这种小鼠体内缺乏成熟的B细胞和T细胞，这两种细胞在免疫反应中发挥着重要作用。实验表明，经过一段时间后，与对照组相比，这种小鼠受伤部位的修复程度明显较差，运动能力的恢复也明显不如对照组。

业内人士表示，这项研究的结果与此前我们的认识完全相反，表明看起来应该避免的免疫反应实际上能够帮助植入的生物材料更好地完成机体修复。这一研究不仅可以更好地指导生物材料的设计与合成，或许还可以启发研究者开发新的疗法。

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2016-08-03 1249857fm32暂无昵称

#生物材#

23 0
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2016-04-28 dongjia2013

#生物材料#

28 0
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2016-04-27 1de11f7fm56(暂无匿称)

学习了一下新知识

96 0
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2016-04-27 吴教授

免疫排斥依然存在

119 0
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2016-04-27 老段

对，亦敌亦友

81 0
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2016-04-26 为何

亦敌亦友

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