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JACC：大样本研究显示先心病外科术后远期死亡率仍居高不下

2018-05-26 MedSci MedSci原创

心血管先心病外科远期
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先天性心脏病外科手术治疗能明显提高复杂先心病的生存率，但其远期的预后效果尚未阐明。本研究纳入了美国儿童心脏病数据库中的35998名接受了首次先心病外科手术治疗且存活下来的年龄小于21岁的患者，经过平均18年时间的随访，有3191名患者出现了死亡，标准化死亡率（SMR）为8.3（95% [CI]： 8.0 - 8.7），15年的SMR从早期的12.7（1982-1992）下降至晚期的10（1998-

先天性心脏病外科手术治疗能明显提高复杂先心病的生存率，但其远期的预后效果尚未阐明。本研究纳入了美国儿童心脏病数据库中的35998名接受了首次先心病外科手术治疗且存活下来的年龄小于21岁的患者，经过平均18年时间的随访，有3191名患者出现了死亡，标准化死亡率（SMR）为8.3（95% [CI]： 8.0 - 8.7），15年的SMR从早期的12.7（1982-1992）下降至晚期的10（1998-2003），即使在非严重的先心病患者如动脉导管未闭和房间隔缺损，SMR依旧处于较高水平，而SMR降低最明显的疾病是大动脉转位（11.0 vs 3.8；p＜0.05）、完全性房室通道（31.3 vs 15.3； p＜0.05）和单心室（53.7vs 37.3；p＜0.05）。研究结果显示，各种类型的先天性心脏病外科术后的远期死亡率均较高，对于某些复杂的先心病，患者的远期死亡率逐年下降，但仍处于较高水平。原始出处：Logan G et al.Trends in Long-Term Mortality After Congenital Heart Surgery.JACC.2018 May.本文系梅

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    2018-11-23 hbwxf

    #JACC#

    0

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    2018-08-29 zhzhxiang

    #样本#

    0

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    2018-05-28 ssnine

    #先心病#

    0

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    2018-05-28 12498568m50暂无昵称

    #ACC#

    0

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    2018-05-27 一天没事干

    很好的学习机会

    0

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    2018-05-26 131****1460

    学习了受益匪浅

    0

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    2018-05-26 清风拂面

    谢谢分享学习

    0

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