感染

订阅

MedSci主页 / 所有栏目 / 感染

Exp Ther Med：细菌素或可用于预防及治疗整形术后的感染

2018-04-01 MedSci MedSci原创

细菌素整形手术感染
关注

整形外科手术后感染是一种严重并发症，严重影响患者的健康。本研究旨在探讨兔模型中鼠李糖乳杆菌来源的细菌素对膝关节置换术后金黄色葡萄球菌感染的抗菌作用。在细菌素注射后1,2,3,4和5天收集血样，并使用商业ELISA试剂盒评估C-反应蛋白（CRP）和白细胞介素（IL）-6水平。另外，通过荧光显微镜评估生物膜的形成。结果显示，术后和感染后，细菌素可明显抑制金黄色葡萄球菌生物膜形成，并降低血清中的CRP和

整形外科手术后感染是一种严重并发症，严重影响患者的健康。本研究旨在探讨兔模型中鼠李糖乳杆菌来源的细菌素对膝关节置换术后金黄色葡萄球菌感染的抗菌作用。

在细菌素注射后1,2,3,4和5天收集血样，并使用商业ELISA试剂盒评估C-反应蛋白（CRP）和白细胞介素（IL）-6水平。另外，通过荧光显微镜评估生物膜的形成。

结果显示，术后和感染后，细菌素可明显抑制金黄色葡萄球菌生物膜形成，并降低血清中的CRP和IL-6的水平（与对照组相比，所有P <0.05）。

综上所述，该研究的结果表明，细菌素是预防整形术后感染的一种潜在药剂。

原始出处：

Zhou B, Zhang D. Antibacterial effects of bacteriocins isolated from Lactobacillus rhamnosus (ATCC 53103) in a rabbit model of knee implant infection. Exp Ther Med. 2018 Mar;15(3):2985-2989. doi: 10.3892/etm.2018.5790. Epub 2018 Jan 24.

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2085456, encodeId=3faf208545669, content=<a href='/topic/show?id=111fe8126dc' target=_blank style='color:#2F92EE;'>#细菌素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78126, encryptionId=111fe8126dc, topicName=细菌素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Sun Jul 15 19:37:00 CST 2018, time=2018-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045264, encodeId=9d39204526403, content=<a href='/topic/show?id=667e5e838e9' target=_blank style='color:#2F92EE;'>#整形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57838, encryptionId=667e5e838e9, topicName=整形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Apr 06 17:37:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608701, encodeId=4dae1608e01ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Apr 03 05:37:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301770, encodeId=3e9a301e703d, content=术后和感染后.细菌素可明显抑制金黄色葡萄球菌生物膜形成, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sun Apr 01 14:59:52 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-07-15 smlt2008

    #细菌素#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2085456, encodeId=3faf208545669, content=<a href='/topic/show?id=111fe8126dc' target=_blank style='color:#2F92EE;'>#细菌素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78126, encryptionId=111fe8126dc, topicName=细菌素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Sun Jul 15 19:37:00 CST 2018, time=2018-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045264, encodeId=9d39204526403, content=<a href='/topic/show?id=667e5e838e9' target=_blank style='color:#2F92EE;'>#整形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57838, encryptionId=667e5e838e9, topicName=整形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Apr 06 17:37:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608701, encodeId=4dae1608e01ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Apr 03 05:37:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301770, encodeId=3e9a301e703d, content=术后和感染后.细菌素可明显抑制金黄色葡萄球菌生物膜形成, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sun Apr 01 14:59:52 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-04-06 gaoxiaoe

    #整形术#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2085456, encodeId=3faf208545669, content=<a href='/topic/show?id=111fe8126dc' target=_blank style='color:#2F92EE;'>#细菌素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78126, encryptionId=111fe8126dc, topicName=细菌素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Sun Jul 15 19:37:00 CST 2018, time=2018-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045264, encodeId=9d39204526403, content=<a href='/topic/show?id=667e5e838e9' target=_blank style='color:#2F92EE;'>#整形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57838, encryptionId=667e5e838e9, topicName=整形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Apr 06 17:37:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608701, encodeId=4dae1608e01ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Apr 03 05:37:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301770, encodeId=3e9a301e703d, content=术后和感染后.细菌素可明显抑制金黄色葡萄球菌生物膜形成, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sun Apr 01 14:59:52 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-04-03 ms3994565386320060

    #Med#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2085456, encodeId=3faf208545669, content=<a href='/topic/show?id=111fe8126dc' target=_blank style='color:#2F92EE;'>#细菌素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78126, encryptionId=111fe8126dc, topicName=细菌素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c39f145, createdName=smlt2008, createdTime=Sun Jul 15 19:37:00 CST 2018, time=2018-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2045264, encodeId=9d39204526403, content=<a href='/topic/show?id=667e5e838e9' target=_blank style='color:#2F92EE;'>#整形术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=57838, encryptionId=667e5e838e9, topicName=整形术)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Fri Apr 06 17:37:00 CST 2018, time=2018-04-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608701, encodeId=4dae1608e01ac, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Tue Apr 03 05:37:00 CST 2018, time=2018-04-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301770, encodeId=3e9a301e703d, content=术后和感染后.细菌素可明显抑制金黄色葡萄球菌生物膜形成, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUlbw1Mf1vppicGcaWPx1YUOgLgKccao77Rykbx3jiazqzwcyXMdzRIZkhFyBPqknibeuOGhXI1VzVg/0, createdBy=7f162154630, createdName=沙漠浪人, createdTime=Sun Apr 01 14:59:52 CST 2018, time=2018-04-01, status=1, ipAttribution=)]
    2018-04-01 沙漠浪人

    术后和感染后.细菌素可明显抑制金黄色葡萄球菌生物膜形成

    0