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Brit J Surg：生活方式变化减轻术前体重对手术结局的影响

2018-10-19 xing.T MedSci原创

生活方式变化减轻术前体重手术结局影响
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由此可见，术前体重减轻具有益处，但不会改变术后发病率或死亡率风险。

近日，外科疾病领域权威杂志British Journal of Surgery上发表了一篇研究文章，该研究的目的是调查术前体重减轻是否会改善临床显著肥胖的外科患者临床结果。

这是一项针对RCT和队列研究的系统评价和综合数据荟萃分析。研究人员对PubMed、MEDLINE、Embase和CINAHL Plus数据库进行了检索，检索时间从数据库成立至到2018年2月。准入标准是：评估减肥干预措施（伴有或不伴有运动的低能量饮食）对接受任何外科手术的患者临床结局影响的研究。在荟萃分析中提取并合成30天或全因住院死亡率的数据。还评估了术后血栓栓塞并发症、手术持续时间、感染和住院时间。

该研究共确定了来自欧洲和北美中心的4项随机对照试验和12项队列研究中的6060名患者。汇总效应估计表明，术前体重减轻计划是有效的，与对照组相比，体重显著减轻：平均差异为-7.42（95％CI为-10.09至-4.74）kg（P <0.001）。术前体重减轻干预与围手术期死亡率降低无关（比值比为1.41,95％CI为0.24~8.40; I2=0％，P=0.66），事件发生率较低。减肥组住院时间缩短（减少27％）。没有发现发病率的差异。

由此可见，术前体重减轻具有益处，但不会改变术后发病率或死亡率风险。

原始出处：

M. Roman,et al. Meta‐analysis of the influence of lifestyle changes for preoperative weight loss on surgical outcomes. British Journal of Surgery.2018. https://doi.org/10.1002/bjs.11001

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    2018-10-22 12282355m97暂无昵称

    学习了

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    2018-10-21 12282355m97暂无昵称

    学习了

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  3. [GetPortalCommentsPageByObjectIdResponse(id=350167, encodeId=6c0c35016ecb, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0af42337291, createdName=12282355m97暂无昵称, createdTime=Mon Oct 22 17:10:06 CST 2018, time=2018-10-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350003, encodeId=c1d835000332, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0af42337291, createdName=12282355m97暂无昵称, createdTime=Sun Oct 21 01:03:17 CST 2018, time=2018-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=349865, encodeId=5c01349865b6, content=谢谢分享，学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Fri Oct 19 21:38:24 CST 2018, time=2018-10-19, status=1, ipAttribution=)]
    2018-10-19 changjiu

    谢谢分享，学习一下谢谢

    0