CGH:炎症性肠炎会影响试管婴儿成功率吗?

2015-04-08 Mechront 译 MedSci原创

炎症性肠炎(IBD)会对育龄期女性造成多个方面的困扰,近期OzaSS等人进行了一项研究,关注炎症性肠炎(IBD)对女性试管婴儿孕育情况的影响。

炎症性肠炎(IBD)会对育龄期女性造成多个方面的困扰,近期OzaSS等人进行了一项研究,关注炎症性肠炎(IBD)对女性试管婴儿孕育情况的影响。

该研究纳入了49名克罗恩病(CD)女性,71名溃疡性结肠炎(UC)女性,还有1名炎症性肠炎未分类的女性,470名没有炎症性肠炎的女性作为对照。在研究期间对她们进行试管婴儿操作(IVF)。

研究结果显示,对照组(non-IBD)试管婴儿累积活产率为53%;溃疡性结肠炎组(UC)累积活产率为69%,相比对照组,P=0.08;克罗恩病组(CD)累积活产率为57%,相比对照组,P=0.87。在三组中相似,对照组(non-IBD) 第一个试管婴儿周期后的妊娠率为40.9%;溃疡性结肠炎组(UC)妊娠率为49.3%,P=0.18;克罗恩病组(CD)妊娠率为42.9%,P=0.79。该数据在三组中无差异。同样第一个试管婴儿周期后的活产率在三组中相似。对照组(non-IBD)该数据为30.2%;溃疡性结肠炎组(UC)为33.8%,P=0.54;克罗恩病组(CD)为30.6%,P=0.95。

研究结果表明,伴有炎症性肠炎的不孕女性其试管婴儿的成功率能达到普通不孕女性的平均水平,即是说炎症性肠炎不会对育龄期女性行试管婴儿产生较大影响。

原始出处:


OzaSS, Pabby V, Dodge LE, et al. In Vitro Fertilization in Women with Inflammatory
Bowel Disease is as Successful as inWomen from the General Infertility
Population
. Clin Gastroenterol Hepatol. 2015

本文系Medsci原创编译整理!转载需要先获得授权,并附原文链接。谢谢!


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    2015-07-16 ying_wu
  2. [GetPortalCommentsPageByObjectIdResponse(id=1813125, encodeId=35cf18131258c, content=<a href='/topic/show?id=1fdd91e56f7' target=_blank style='color:#2F92EE;'>#试管婴#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91756, encryptionId=1fdd91e56f7, topicName=试管婴)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=11b4465, createdName=ying_wu, createdTime=Thu Jul 16 08:08:00 CST 2015, time=2015-07-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=37560, encodeId=cf3d3e5607b, content=这个病例很难搜集吧?, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhRUzmFEmHvdIaOns4DmF3BicVffXjkOjBTiaMUIA4o7feGvE5IJ0SfSco4ib955Rx7bvWlib7j9V15xp/0, createdBy=814d1631326, createdName=cmn, createdTime=Tue Sep 29 19:13:00 CST 2015, time=2015-09-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2058352, encodeId=65aa20583522b, content=<a href='/topic/show?id=f6ba4546d1' target=_blank style='color:#2F92EE;'>#CGH#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4546, encryptionId=f6ba4546d1, topicName=CGH)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8994206, createdName=chendoc242, createdTime=Thu Apr 09 06:08:00 CST 2015, time=2015-04-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1547007, encodeId=0013154e0073a, content=<a href='/topic/show?id=4ef26e01766' target=_blank style='color:#2F92EE;'>#炎症性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67017, encryptionId=4ef26e01766, topicName=炎症性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=09e813968720, createdName=12498dd9m15暂无昵称, createdTime=Fri Apr 10 12:08:00 CST 2015, time=2015-04-10, status=1, ipAttribution=)]
    2015-09-29 cmn

    这个病例很难搜集吧?

    0

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    2015-04-09 chendoc242
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