Nutrition and Metabolic Insights:“解酒神药”获批上市,1小时内分解70%酒精,100%天然成分,预防宿醉

2022-07-12 王聪 “生物世界”

乙醛的产生导致了喝酒后的脸红、头痛、恶心、心跳加快,以及令人难受的宿醉,更重要的是,体内产生的乙醛还有致癌作用,增加胃肠道癌症和肝癌等癌症发病风险。

众所周知,喝酒之后,酒精(乙醇)会被胃肠道吸收而进入血液,然后通过血液循环到达肝脏,在肝脏中,乙醇脱氢酶(ADH)负责将乙醇(酒精)催化为乙醛,乙醛脱氢酶(ALDH)负责将产生的乙醛进一步催化为乙酸。

乙醛的产生导致了喝酒后的脸红、头痛、恶心、心跳加快,以及令人难受的宿醉,更重要的是,体内产生的乙醛还有致癌作用,增加胃肠道癌症和肝癌等癌症发病风险。

许多研究告诉我们喝酒对健康的危害,例如国际顶尖医学期刊《柳叶刀》于2018年发表的一项大规模研究显示,酒精是全球15至49岁男性和女性患病和早逝的主要风险因素,全球近十分之一人口的死亡是饮酒所致。该研究得出的结论是:对健康危害最小的饮酒量就是完全不饮酒。

但让所有人都完全不喝酒,显然是一件不现实的事,那么是否可以通过某些方式降低喝酒带来的伤害呢?

2022年7月4日,英国上市了一款“解酒神药”——Myrkl,作为一种食品补充剂销售,号称史上首款有效分解酒精的产品。它是由瑞典的益生菌公司 DeFaire Medical 开发,每盒售价30英镑,包含30粒胶囊,每次服用两粒(约合16元人民币)。它的主要成分是两种肠道细菌——枯草芽孢杆菌和凝结芽孢杆菌在内的细菌菌株,并添加了L-半胱氨酸和维生素B12,以及发酵米糠、糊精、脂肪酸镁盐和磷酸钙等其他物质。

在喝酒之前1-12小时服用,在喝酒后,这两种细菌会在酒精进入血液和肝脏前将其迅速分解为二氧化碳和水,从而减少有害的乙醛的产生。

Myrkl 的上市,基于一项小规模人体临床试验,该临床试验结果于2022年6月23日发表在了 Nutrition and Metabolic Insights 期刊上。

在这项针对24名健康的白人受试者的小型双盲对照临床试验中,受试者在一周时间里每天服用 Myrkl 或安慰剂,然后进行喝烈酒(酒精度为40%)的测试。

结果显示,在喝酒后30分钟,服用 Myrkl 的实验组血液中的酒精含量相比服用安慰剂的对照组的下降50%左右。在60分钟时,两组之间的差距扩大到了70%左右。实验组平均在2小时后血液酒精水平降为零,对照组则需要3小时。

但需要指出的是,这项临床试验并没有追踪受试者的乙醛或乙酸水平,因此,还不清楚该公司所宣传的 Myrkl 降低肝脏产生乙醛和乙酸水平是如何得出的。

这项临床试验显示,服用 Myrkl 后,喝2-3杯标准杯的烈酒(英国的1标准杯指10ml酒精),你只会感受到1-2杯的效果。

需要强调的是,Myrkl 可能并不会减少酒精对胃肠道系统的伤害,只是让肠道细菌分解了部分酒精,从而减少了进入血液的酒精量,在这种意义上,其实是浪费了你花钱买来的酒(哈哈)。

2021年7月,《柳叶刀·肿瘤学》发表了世界卫生组织国际癌症研究机署(IARC)领导的一项大型研究研。该研究指出,2020年有超过74万人因喝酒导致癌症,即使是少量饮酒也会明显增加癌症发病率。

因此,把酒精饮料换成水,能够实质性减少血液酒精含量、消除宿醉症状,防止酒精带来的致癌作用。这种“解酒药”实际上可能会导致原本喝不了那么多酒的人喝更多的酒,这显然不是一件好事。

但当我打开 Myrkl 的网站时,大大的“SOLD OUT”映入眼帘,第一批产品已经售罄,说明人们对它的需求还是很大啊。

 

特别提醒:酒精是一种致癌物,不喝酒更健康。

参考资料:

https://www.myrkl.co.uk/

https://journals.sagepub.com/doi/full/10.1177/11786388221108919

https://newatlas.com/health-wellbeing/myrkl-hangover-pill-alcohol/

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    2023-01-08 紫砂壶
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    2023-03-06 lifestar 来自上海

    2022年7月4日,英国上市了一款“#解酒神药#”——#Myrkl#,作为一种食品补充剂销售,号称史上首款有效分解酒精的产品。它是由瑞典的#益生菌#公司 DeFaire Medical 开发,每盒售价30英镑,包含30粒胶囊,每次服用两粒(约合16元人民币)。它的主要成分是两种肠道细菌——#枯草芽孢杆菌##凝结芽孢杆菌#在内的细菌菌株,并添加了#L-半胱氨酸#和维生素B12,以及发酵米糠、糊精、脂肪酸镁盐和磷酸钙等其他物质。

    0

  4. 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    2023-06-20 weiz
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target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Jul 20 12:10:36 CST 2022, time=2022-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888447, encodeId=2752188844e88, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Dec 17 23:10:36 CST 2022, time=2022-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1234036, encodeId=ba0a12340369d, content=厉害厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=969d2873055, createdName=走,走走, createdTime=Fri Jul 22 15:10:20 CST 2022, time=2022-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598173, encodeId=14ac15981e3c2, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Jul 13 09:10:36 CST 2022, time=2022-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1232019, encodeId=133f1232019c1, content=科技改变生活<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/gKNgZiaia7XBE8lJLn1fp5u443yIhUNiaN9RztibctRREAGYVEtL7eC22wG0DzYdDiaiaTAEg4HaotaF4icegqk4VQvCA/132, createdBy=d6182579909, createdName=西瓜0628, createdTime=Tue Jul 12 15:53:15 CST 2022, time=2022-07-12, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1764121, encodeId=10a21e6412153, content=<a href='/topic/show?id=f91a9105385' target=_blank style='color:#2F92EE;'>#解酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91053, encryptionId=f91a9105385, topicName=解酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a85837628422, createdName=紫砂壶, createdTime=Sun Jan 08 09:10:36 CST 2023, time=2023-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661729, encodeId=32a91661e2991, content=<a href='/topic/show?id=1b3c1315481' target=_blank style='color:#2F92EE;'>#nutrition#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13154, encryptionId=1b3c1315481, topicName=nutrition)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6f0d25331316, createdName=膀胱癌, createdTime=Sun Jul 24 07:10:36 CST 2022, time=2022-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2117841, encodeId=4bf1211e841c9, content=2022年7月4日,英国上市了一款“<a href='/topic/show?id=5a9e105429bd' target=_blank style='color:#2F92EE;'>#解酒神药#</a>”——<a href='/topic/show?id=87111054307a' target=_blank style='color:#2F92EE;'>#Myrkl#</a>,作为一种食品补充剂销售,号称史上首款有效分解酒精的产品。它是由瑞典的<a href='/topic/show?id=5d0ee2249b0' target=_blank style='color:#2F92EE;'>#益生菌#</a>公司 DeFaire Medical 开发,每盒售价30英镑,包含30粒胶囊,每次服用两粒(约合16元人民币)。它的主要成分是两种肠道细菌——<a href='/topic/show?id=23f4105431fe' target=_blank style='color:#2F92EE;'>#枯草芽孢杆菌#</a>和<a href='/topic/show?id=b53d105432fd' target=_blank style='color:#2F92EE;'>#凝结芽孢杆菌#</a>在内的细菌菌株,并添加了<a href='/topic/show?id=dc30105433fa' target=_blank style='color:#2F92EE;'>#L-半胱氨酸#</a>和维生素B12,以及发酵米糠、糊精、脂肪酸镁盐和磷酸钙等其他物质。, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=105429, encryptionId=5a9e105429bd, topicName=解酒神药), TopicDto(id=105430, encryptionId=87111054307a, topicName=Myrkl), TopicDto(id=72249, encryptionId=5d0ee2249b0, topicName=益生菌), TopicDto(id=105431, encryptionId=23f4105431fe, topicName=枯草芽孢杆菌), TopicDto(id=105432, encryptionId=b53d105432fd, topicName=凝结芽孢杆菌), TopicDto(id=105433, encryptionId=dc30105433fa, topicName=L-半胱氨酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Mar 06 02:59:19 CST 2023, time=2023-03-06, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1632627, encodeId=2fe2163262edd, content=<a href='/topic/show?id=aa0488034a0' target=_blank style='color:#2F92EE;'>#获批上市#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88034, encryptionId=aa0488034a0, topicName=获批上市)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=820f21933891, createdName=weiz, createdTime=Tue Jun 20 05:10:36 CST 2023, time=2023-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2029731, encodeId=b6ba2029e310a, content=<a href='/topic/show?id=27fd11593c6' target=_blank style='color:#2F92EE;'>#metabolic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11593, encryptionId=27fd11593c6, topicName=metabolic)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Apr 02 15:10:36 CST 2023, time=2023-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1897034, encodeId=1f53189e0341f, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Jul 20 12:10:36 CST 2022, time=2022-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888447, encodeId=2752188844e88, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Dec 17 23:10:36 CST 2022, time=2022-12-17, status=1, ipAttribution=), 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GetPortalCommentsPageByObjectIdResponse(id=1232019, encodeId=133f1232019c1, content=科技改变生活<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/gKNgZiaia7XBE8lJLn1fp5u443yIhUNiaN9RztibctRREAGYVEtL7eC22wG0DzYdDiaiaTAEg4HaotaF4icegqk4VQvCA/132, createdBy=d6182579909, createdName=西瓜0628, createdTime=Tue Jul 12 15:53:15 CST 2022, time=2022-07-12, status=1, ipAttribution=)]
    2022-07-20 一闲
  7. [GetPortalCommentsPageByObjectIdResponse(id=1764121, encodeId=10a21e6412153, content=<a href='/topic/show?id=f91a9105385' target=_blank style='color:#2F92EE;'>#解酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91053, encryptionId=f91a9105385, topicName=解酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a85837628422, createdName=紫砂壶, createdTime=Sun Jan 08 09:10:36 CST 2023, time=2023-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661729, encodeId=32a91661e2991, content=<a href='/topic/show?id=1b3c1315481' target=_blank style='color:#2F92EE;'>#nutrition#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13154, encryptionId=1b3c1315481, topicName=nutrition)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicName=null, topicId=null, topicList=[TopicDto(id=105429, encryptionId=5a9e105429bd, topicName=解酒神药), TopicDto(id=105430, encryptionId=87111054307a, topicName=Myrkl), TopicDto(id=72249, encryptionId=5d0ee2249b0, topicName=益生菌), TopicDto(id=105431, encryptionId=23f4105431fe, topicName=枯草芽孢杆菌), TopicDto(id=105432, encryptionId=b53d105432fd, topicName=凝结芽孢杆菌), TopicDto(id=105433, encryptionId=dc30105433fa, topicName=L-半胱氨酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aa0e14, createdName=lifestar, createdTime=Mon Mar 06 02:59:19 CST 2023, time=2023-03-06, status=1, ipAttribution=上海), GetPortalCommentsPageByObjectIdResponse(id=1632627, encodeId=2fe2163262edd, content=<a href='/topic/show?id=aa0488034a0' target=_blank style='color:#2F92EE;'>#获批上市#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88034, encryptionId=aa0488034a0, topicName=获批上市)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=820f21933891, createdName=weiz, createdTime=Tue Jun 20 05:10:36 CST 2023, time=2023-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2029731, encodeId=b6ba2029e310a, content=<a href='/topic/show?id=27fd11593c6' target=_blank style='color:#2F92EE;'>#metabolic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11593, encryptionId=27fd11593c6, topicName=metabolic)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Apr 02 15:10:36 CST 2023, time=2023-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1897034, encodeId=1f53189e0341f, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Jul 20 12:10:36 CST 2022, time=2022-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888447, encodeId=2752188844e88, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Dec 17 23:10:36 CST 2022, time=2022-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1234036, encodeId=ba0a12340369d, content=厉害厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=969d2873055, createdName=走,走走, createdTime=Fri Jul 22 15:10:20 CST 2022, time=2022-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598173, encodeId=14ac15981e3c2, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Jul 13 09:10:36 CST 2022, time=2022-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1232019, encodeId=133f1232019c1, content=科技改变生活<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/gKNgZiaia7XBE8lJLn1fp5u443yIhUNiaN9RztibctRREAGYVEtL7eC22wG0DzYdDiaiaTAEg4HaotaF4icegqk4VQvCA/132, createdBy=d6182579909, createdName=西瓜0628, createdTime=Tue Jul 12 15:53:15 CST 2022, time=2022-07-12, status=1, ipAttribution=)]
    2022-12-17 guojianrong
  8. 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target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Jul 20 12:10:36 CST 2022, time=2022-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888447, encodeId=2752188844e88, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Dec 17 23:10:36 CST 2022, time=2022-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1234036, encodeId=ba0a12340369d, content=厉害厉害, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=969d2873055, createdName=走,走走, createdTime=Fri Jul 22 15:10:20 CST 2022, time=2022-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1598173, encodeId=14ac15981e3c2, content=<a href='/topic/show?id=6c6f1e62c5' target=_blank style='color:#2F92EE;'>#ABO#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1762, encryptionId=6c6f1e62c5, topicName=ABO)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6c918580135, createdName=闆锋旦, createdTime=Wed Jul 13 09:10:36 CST 2022, time=2022-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1232019, encodeId=133f1232019c1, content=科技改变生活<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/gKNgZiaia7XBE8lJLn1fp5u443yIhUNiaN9RztibctRREAGYVEtL7eC22wG0DzYdDiaiaTAEg4HaotaF4icegqk4VQvCA/132, createdBy=d6182579909, createdName=西瓜0628, createdTime=Tue Jul 12 15:53:15 CST 2022, time=2022-07-12, status=1, ipAttribution=)]
    2022-07-22 走,走走

    厉害厉害

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1764121, encodeId=10a21e6412153, content=<a href='/topic/show?id=f91a9105385' target=_blank style='color:#2F92EE;'>#解酒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91053, encryptionId=f91a9105385, topicName=解酒)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a85837628422, createdName=紫砂壶, createdTime=Sun Jan 08 09:10:36 CST 2023, time=2023-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661729, encodeId=32a91661e2991, content=<a href='/topic/show?id=1b3c1315481' target=_blank style='color:#2F92EE;'>#nutrition#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13154, encryptionId=1b3c1315481, topicName=nutrition)], attachment=null, authenticateStatus=null, createdAvatar=null, 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authenticateStatus=null, createdAvatar=null, createdBy=820f21933891, createdName=weiz, createdTime=Tue Jun 20 05:10:36 CST 2023, time=2023-06-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2029731, encodeId=b6ba2029e310a, content=<a href='/topic/show?id=27fd11593c6' target=_blank style='color:#2F92EE;'>#metabolic#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11593, encryptionId=27fd11593c6, topicName=metabolic)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eqySEUYKeYDjXJMYMrtscBNkpAnLfQZgDcdkEratcJPqS7ARJOXqllZQhCSFicErlBFbIywuoiaP0LQ/132, createdBy=012d2500132, createdName=ms5880526374914242, createdTime=Sun Apr 02 15:10:36 CST 2023, time=2023-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1897034, encodeId=1f53189e0341f, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Jul 20 12:10:36 CST 2022, time=2022-07-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1888447, encodeId=2752188844e88, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sat Dec 17 23:10:36 CST 2022, time=2022-12-17, status=1, ipAttribution=), 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GetPortalCommentsPageByObjectIdResponse(id=1232019, encodeId=133f1232019c1, content=科技改变生活<a href='/topic/show?id=23e3454e353' target=_blank style='color:#2F92EE;'>#学习#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45473, encryptionId=23e3454e353, topicName=学习)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/gKNgZiaia7XBE8lJLn1fp5u443yIhUNiaN9RztibctRREAGYVEtL7eC22wG0DzYdDiaiaTAEg4HaotaF4icegqk4VQvCA/132, createdBy=d6182579909, createdName=西瓜0628, createdTime=Tue Jul 12 15:53:15 CST 2022, time=2022-07-12, status=1, ipAttribution=)]
    2022-07-13 闆锋旦
  10. 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    2022-07-12 西瓜0628

    科技改变生活#学习#

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