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JAMA Psychiatry：自身免疫病与严重感染者易发心境障碍

2013-06-27 姜珊 编译 中国医学论坛报

自身免疫病心境障碍
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丹麦和美国联合研究表明，自身免疫病和感染是心境障碍的危险因素。论文6月12日在线发表于《美国医学会杂志·精神病学》（JAMA Psychiatry）。 研究纳入1945至1996年间出生者356万人，自1977年1月1日随访至2010年12月31日。主要终点为首发心境障碍风险。结果为，共91637例发生心境障碍。自身免疫病和感染住院史分别使随后心境障碍诊断的风险增加45%[发病

丹麦和美国联合研究表明，自身免疫病和感染是心境障碍的危险因素。论文6月12日在线发表于《美国医学会杂志·精神病学》（JAMA Psychiatry）。

研究纳入1945至1996年间出生者356万人，自1977年1月1日随访至2010年12月31日。主要终点为首发心境障碍风险。结果为，共91637例发生心境障碍。自身免疫病和感染住院史分别使随后心境障碍诊断的风险增加45%[发病率比（IRR)=1.45]和62%（IRR=1.62）。两个危险因素协同作用，进一步增加随后心境障碍风险（IRR=2.35）。确诊心境障碍者，约1/3曾因感染于医院就诊，5%有自身免疫病史。



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    2013-08-28 fengxx

    #心境障碍#

    0

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    2013-10-08 heli0118

    #免疫病#

    0

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    2013-09-01 diushouji

    #Psychiatry#

    0

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    2013-06-29 tonychen21

    #自身免疫病#

    0

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    2013-06-29 智智灵药

    #严重感染#

    0