2019年AACR年会:Syros将展示选择性CDK7抑制剂SY-1365的全新临床前数据

2019-02-28 不详 网络

Syros制药公司是控制基因表达的药物开发领域的领导者,近日宣布将在美国癌症研究协会(AACR)年会上展示SY-1365的最新临床前数据,SY-1365是其首个选择性细胞周期蛋白依赖性激酶7(CDK7)抑制剂,目前正在进行针对卵巢癌和乳腺癌的I期临床试验。关于SY-1365的报告将突出显示SY-1365对高级别浆液性卵巢癌患者来源的异种移植模型的反应。

Syros制药公司是控制基因表达的药物开发领域的领导者,近日宣布将在美国癌症研究协会(AACR)年会上展示SY-1365的最新临床前数据,SY-1365是其首个选择性细胞周期蛋白依赖性激酶7CDK7)抑制剂,目前正在进行针对卵巢癌乳腺癌I临床试验。关于SY-1365的报告将突出显示SY-1365对高级别浆液性卵巢癌患者来源的异种移植模型的反应。

卵巢癌是发源自女性卵巢的癌症,会产生会入侵以及转移到其他部位的异常细胞。卵巢癌初期症状不明显,随病情进展,才会出现许多癌症的典型症状,包括胀气、腹胀、骨盆痛等。癌症较容易扩散到腹膜、淋巴结、肺脏、肝脏等部位。2012年全世界共有239千名女性罹患卵巢癌,造成152***死亡。是癌症中罹患人数第七多的癌症,也是造成女性死亡癌症中的第八位。卵巢癌在北美洲及欧洲较盛行,比在非洲及亚洲要常见。


原始出处:

http://www.firstwordpharma.com/node/1627246#axzz5gj4KGYJT

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    2019-04-03 jklm09
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    2019-03-02 lsndxfj
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    2019-03-02 heli0118
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    2019-03-02 zhouqu_8
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    2019-03-02 Luyuxie_14